Dylan M Dean
Overview
Explore the profile of Dylan M Dean including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
335
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Recent Articles
1.
Dean D, Rago A, Morgan J
Cell Motil Cytoskeleton
. 2009 Jan;
66(3):129-41.
PMID: 19170224
Cytoskeletal tension is fundamental to many biological processes, including germ layer sorting during embryogenesis [Krieg et al., 2008]. In vitro, such tension influences cell sorting in self-assembled, 3D microtissues and...
2.
Rago A, Dean D, Morgan J
Biotechnol Bioeng
. 2008 Nov;
102(4):1231-41.
PMID: 19012266
Tissue fusion and cell sorting are processes fundamental to developmental biology with applications in tissue engineering. We have designed a fusion assay to investigate the factors governing the fusion of...
3.
Rago A, Napolitano A, Dean D, Chai P, Morgan J
Cytotechnology
. 2008 Nov;
56(2):81-90.
PMID: 19002845
Anoikis is a specific form of apoptosis resulting from the loss of cellular attachment to extracellular matrix or other cells. Challenges in simulating these conditions in vitro make it difficult...
4.
Dean D, Morgan J
Tissue Eng Part A
. 2008 Aug;
14(12):1989-97.
PMID: 18673088
The ability of cells to self-assemble into a microtissue such as a spheroid has been attributed mainly to intercellular cohesiveness achieved by the binding of surface membrane proteins such as...
5.
Napolitano A, Dean D, Man A, Youssef J, Ho D, Rago A, et al.
Biotechniques
. 2007 Nov;
43(4):494, 496-500.
PMID: 18019341
Techniques that allow cells to self-assemble into three-dimensional (3-D) spheroid microtissues provide powerful in vitro models that are becoming increasingly popular--especially in fields such as stem cell research, tissue engineering,...
6.
Dean D, Napolitano A, Youssef J, Morgan J
FASEB J
. 2007 Jul;
21(14):4005-12.
PMID: 17627028
It is thought that, due to energy and surface area:volume minimization, the spheroid is the terminal structure of cellular self-assembly. We investigated whether self-assembly could be directed to generate complex-shaped...
7.
Napolitano A, Chai P, Dean D, Morgan J
Tissue Eng
. 2007 May;
13(8):2087-94.
PMID: 17518713
The process by which cells self-assemble to form three-dimensional (3D) structures is central to morphogenesis and development of living tissues and hence is of growing interest to the field of...
8.
Dean D, Nguitragool W, Miri A, McCabe S, Zimmerman A
Proc Natl Acad Sci U S A
. 2002 May;
99(12):8372-7.
PMID: 12034887
In retinal rods, light-induced isomerization of 11-cis-retinal to all-trans-retinal within rhodopsin triggers an enzyme cascade that lowers the concentration of cGMP. Consequently, cyclic nucleotide-gated (CNG) ion channels close, generating the...