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Dylan Clark-Boucher

Explore the profile of Dylan Clark-Boucher including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Clark-Boucher D, Miller J
J Comput Graph Stat . 2025 Mar; 34(1):374-383. PMID: 40041743
Principal variables analysis (PVA) is a technique for selecting a subset of variables that capture as much of the information in a dataset as possible. Existing approaches for PVA are...
2.
Clark-Boucher D, Coull B, Reeder H, Wang F, Sun Q, Starr J, et al.
ArXiv . 2025 Feb; PMID: 39936028
A key challenge in differential abundance analysis of microbial samples is that the counts for each sample are compositional, resulting in biased comparisons of the absolute abundance across study groups....
3.
Clark-Boucher D, Zhou X, Du J, Liu Y, Needham B, Smith J, et al.
PLoS Genet . 2023 Nov; 19(11):e1011022. PMID: 37934796
Epigenetic researchers often evaluate DNA methylation as a potential mediator of the effect of social/environmental exposures on a health outcome. Modern statistical methods for jointly evaluating many mediators have not...
4.
Salvatore M, Clark-Boucher D, Fritsche L, Ortlieb J, Houghtby J, Driscoll A, et al.
Epidemiol Health . 2023 Aug; 45:e2023074. PMID: 37591787
The Epidemiologic Questionnaire (EPI-Q) was established to collect broad, uniform, self-reported health data to supplement electronic health record (EHR) and genotype information from participants in the University of Michigan (UM)...
5.
Clark-Boucher D, Zhou X, Du J, Liu Y, Needham B, Smith J, et al.
medRxiv . 2023 Feb; PMID: 36824903
Epigenetic researchers often evaluate DNA methylation as a mediator between social/environmental exposures and disease, but modern statistical methods for jointly evaluating many mediators have not been widely adopted. We compare...
6.
Du J, Zhou X, Clark-Boucher D, Hao W, Liu Y, Smith J, et al.
Genet Epidemiol . 2022 Dec; 47(2):167-184. PMID: 36465006
Mediation hypothesis testing for a large number of mediators is challenging due to the composite structure of the null hypothesis, ( : effect of the exposure on the mediator after...
7.
Clark-Boucher D, Boss J, Salvatore M, Smith J, Fritsche L, Mukherjee B
PLoS One . 2022 Jul; 17(7):e0269017. PMID: 35877617
Since the beginning of the Coronavirus Disease 2019 (COVID-19) pandemic, a focus of research has been to identify risk factors associated with COVID-19-related outcomes, such as testing and diagnosis, and...