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Dustin J Sokolowski

Explore the profile of Dustin J Sokolowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 30
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Recent Articles
1.
Tracey L, El-Maklizi M, Sokolowski D, Gams M, Brooke-Bisschop T, Ruston J, et al.
Sci Rep . 2025 Mar; 15(1):8827. PMID: 40087379
The transcription factor Prdm14 is a potent oncogene implicated in the initiation of many cancers. PRDM14 resets and maintains the pluripotent state in normal cells, but the molecular mechanisms through...
2.
Sokolowski D, Mai M, Verma A, Morgenshtern G, Subasri V, Naveed H, et al.
NAR Genom Bioinform . 2025 Mar; 7(1):lqaf011. PMID: 40041206
Many regulatory factors impact the expression of individual genes including, but not limited, to microRNA, long non-coding RNA (lncRNA), transcription factors (TFs), methylation, copy number variation (CNV), and single-nucleotide polymorphisms...
3.
Sokolowski D, Miclaus M, Nater A, Faykoo-Martinez M, Hoekzema K, Zuzarte P, et al.
bioRxiv . 2024 Dec; PMID: 39651266
The naked mole-rat (NMR; ) is a eusocial subterranean rodent with a highly unusual set of physiological traits that has attracted great interest amongst the scientific community. However, the genetic...
4.
Feng S, Marhon S, Sokolowski D, DCosta A, Soares F, Mehdipour P, et al.
Nat Commun . 2024 Oct; 15(1):9321. PMID: 39472584
Inactivating mutations in SMARCB1 confer an oncogenic dependency on EZH2 in atypical teratoid rhabdoid tumors (ATRTs), but the underlying mechanism has not been fully elucidated. We found that the sensitivity...
5.
Sokolowski D, Hou H, Yuki K, Roy A, Chan C, Choi W, et al.
Biol Sex Differ . 2024 Oct; 15(1):83. PMID: 39449090
Background: The hypothalamus plays a central role in regulating puberty. However, our knowledge of the postnatal gene regulatory networks that control the pubertal transition in males and females is incomplete....
6.
Reuter M, Sokolowski D, Diaz-Mejia J, Keunen J, de Vrijer B, Chan C, et al.
Commun Biol . 2023 Jul; 6(1):770. PMID: 37481629
Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic left heart syndrome (HLHS). To investigate if a decrease in left heart flow results...
7.
Sokolowski D, Vasquez O, Wilson M, Sokolowski M, Anreiter I
Ann N Y Acad Sci . 2023 Jun; 1526(1):99-113. PMID: 37350250
Genes are often pleiotropic and plastic in their expression, features which increase and diversify the functionality of the genome. The foraging (for) gene in Drosophila melanogaster is highly pleiotropic and...
8.
Sokolowski D, Ahn J, Erdman L, Hou H, Ellis K, Wang L, et al.
NAR Genom Bioinform . 2023 Jan; 5(1):lqad003. PMID: 36694664
Differential gene expression analysis using RNA sequencing (RNA-seq) data is a standard approach for making biological discoveries. Ongoing large-scale efforts to process and normalize publicly available gene expression data enable...
9.
Sokolowski D
J Neurogenet . 2021 Jun; 35(3):104-106. PMID: 34121599
I am often asked how our mother inspired my sister Moriah and me to want to become scientists. She never directly suggested we should go down that path. Instead, she...
10.
Sokolowski D, Faykoo-Martinez M, Erdman L, Hou H, Chan C, Zhu H, et al.
NAR Genom Bioinform . 2021 Mar; 3(1):lqab011. PMID: 33655208
RNA sequencing (RNA-seq) is widely used to identify differentially expressed genes (DEGs) and reveal biological mechanisms underlying complex biological processes. RNA-seq is often performed on heterogeneous samples and the resulting...