Dustin J Flanagan
Overview
Explore the profile of Dustin J Flanagan including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
659
Followers
0
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Recent Articles
1.
Parker C, Chambers A, Flanagan D, Ho J, Collard T, Ngo G, et al.
DNA Repair (Amst)
. 2024 Dec;
145:103800.
PMID: 39657282
No abstract available.
2.
Lim C, Romeo O, Tran B, Flanagan D, Kirby E, McCartney E, et al.
J Med Virol
. 2023 Nov;
95(11):e29232.
PMID: 38009279
The intrahepatic cholangiocyte organoids (ICOs) model was evaluated for host differences in hepatitis B virus (HBV) infection, cellular responses, antiviral and immunomodulator responses. Twelve ICOs generated from liver resections and...
3.
Holt A, Najumudeen A, Collard T, Li H, Millett L, Hoskin A, et al.
Cancer Metab
. 2023 Oct;
11(1):18.
PMID: 37858256
Background: To support proliferation and survival within a challenging microenvironment, cancer cells must reprogramme their metabolism. As such, targeting cancer cell metabolism is a promising therapeutic avenue. However, identifying tractable...
4.
van Driel M, Linssen J, Flanagan D, Vlahov N, Nijman L, de Groot N, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Jun;
16(4):652-655.
PMID: 37364735
No abstract available.
5.
Flanagan D, Amirkhah R, Vincent D, Gunduz N, Gentaz P, Cammareri P, et al.
Nat Commun
. 2023 Jan;
14(1):522.
PMID: 36720858
No abstract available.
6.
Flanagan D, Amirkhah R, Vincent D, Gunduz N, Gentaz P, Cammareri P, et al.
Nat Commun
. 2022 Dec;
13(1):7551.
PMID: 36477656
The pro-tumourigenic role of epithelial TGFβ signalling in colorectal cancer (CRC) is controversial. Here, we identify a cohort of born to be bad early-stage (T1) colorectal tumours, with aggressive features...
7.
Gil Vazquez E, Nasreddin N, Valbuena G, Mulholland E, Belnoue-Davis H, Eggington H, et al.
Cell Stem Cell
. 2022 Nov;
29(11):1612.
PMID: 36332574
No abstract available.
8.
Vasquez E, Nasreddin N, Valbuena G, Mulholland E, Belnoue-Davis H, Eggington H, et al.
Cell Stem Cell
. 2022 Aug;
29(8):1213-1228.e8.
PMID: 35931031
Intestinal homeostasis is underpinned by LGR5+ve crypt-base columnar stem cells (CBCs), but following injury, dedifferentiation results in the emergence of LGR5-ve regenerative stem cell populations (RSCs), characterized by fetal transcriptional...
9.
Azkanaz M, Corominas-Murtra B, Ellenbroek S, Bruens L, Webb A, Laskaris D, et al.
Nature
. 2022 Jul;
607(7919):548-554.
PMID: 35831497
The morphology and functionality of the epithelial lining differ along the intestinal tract, but tissue renewal at all sites is driven by stem cells at the base of crypts. Whether...
10.
Parker C, Chambers A, Flanagan D, Ho J, Collard T, Ngo G, et al.
DNA Repair (Amst)
. 2022 Apr;
115:103331.
PMID: 35468497
The proto-oncogene BCL-3 is upregulated in a subset of colorectal cancers (CRC), where it has been shown to enhance tumour cell survival. However, although increased expression correlates with poor patient...