Duncan Graham
Overview
Explore the profile of Duncan Graham including associated specialties, affiliations and a list of published articles.
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Articles
233
Citations
2710
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Recent Articles
11.
Scullion K, MacIntyre I, Sloan-Dennison S, Clark B, Fineran P, Mair J, et al.
Toxicol Sci
. 2024 Mar;
199(2):203-209.
PMID: 38521541
Drug-induced liver injury (DILI) is a challenge in clinical medicine and drug development. Highly sensitive novel biomarkers have been identified for detecting DILI following a paracetamol overdose. The study objective...
12.
Johnson C, Setterfield M, Hassanain W, Wipat A, Pocock M, Faulds K, et al.
Analyst
. 2024 Jan;
149(5):1527-1536.
PMID: 38265775
Five carbapenemase enzymes, coined the 'big five', have been identified as the biggest threat to worldwide antibiotic resistance based on their broad substrate affinity and global prevalence. Here we show...
13.
Fergusson J, Wallace G, Sloan-Dennison S, Carland R, Shand N, Graham D, et al.
J Phys Chem C Nanomater Interfaces
. 2023 Dec;
127(50):24475-24486.
PMID: 38148849
Owing to their biocompatibility, gold nanoparticles have many applications in healthcare, notably for targeted drug delivery and the photothermal therapy of tumors. The addition of a silica shell to the...
14.
Swiatlowska P, Tipping W, Marhuenda E, Severi P, Fomin V, Yang Z, et al.
Adv Sci (Weinh)
. 2023 Dec;
11(9):e2308686.
PMID: 38145971
Arterial Vascular smooth muscle cells (VSMCs) play a central role in the onset and progression of atherosclerosis. Upon exposure to pathological stimuli, they can take on alternative phenotypes that, among...
15.
Rensonnet A, Tipping W, Malherbe C, Faulds K, Eppe G, Graham D
Analyst
. 2023 Dec;
149(2):553-562.
PMID: 38088863
Hyperspectral stimulated Raman scattering (SRS) microscopy is a powerful method for direct visualisation and compositional analysis of cellular lipid droplets. Here we report the application of spectral phasor analysis as...
16.
Murphy N, Tipping W, Braddick H, Wilson L, Tomkinson N, Faulds K, et al.
Angew Chem Int Ed Engl
. 2023 Oct;
62(48):e202311530.
PMID: 37821742
Multiplex optical detection in live cells is challenging due to overlapping signals and poor signal-to-noise associated with some chemical reporters. To address this, the application of spectral phasor analysis to...
17.
Zhao Y, Patel N, Sun P, Faulds K, Graham D, Liu J
Analyst
. 2023 Oct;
148(22):5612-5618.
PMID: 37819248
Due to their programmable structures, many aptamers can be readily split into two halves while still retaining their target binding function. While split aptamers are prevalent in the biosensor field,...
18.
Masson J, Wallace G, Asselin J, Ten A, Hojjat Jodaylami M, Faulds K, et al.
ACS Appl Mater Interfaces
. 2023 Sep;
15(39):46181-46194.
PMID: 37733583
Surface curvature can be used to focus light and alter optical processes. Here, we show that curved surfaces (spheres, cylinders, and cones) with a radius of around 5 μm lead...
19.
Borek-Dorosz A, Pieczara A, Orleanska J, Brzozowski K, Tipping W, Graham D, et al.
Biochim Biophys Acta Mol Cell Res
. 2023 Sep;
1871(1):119575.
PMID: 37689141
Metabolism of endothelial cells (ECs) depends on the availability of the energy substrates. Since the endothelium is the first line of defence against inflammation in the cardiovascular system and its...
20.
McCabe S, Wallace G, Sloan-Dennison S, Tipping W, Shand N, Graham D, et al.
Analyst
. 2023 Jun;
148(14):3247-3256.
PMID: 37366648
Glioblastoma multiforme (GBM) is a particularly aggressive and high-grade brain cancer, with poor prognosis and life expectancy, in urgent need of novel therapies. These severe outcomes are compounded by the...