Dudley Chung
Overview
Explore the profile of Dudley Chung including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
9
Citations
117
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0
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Recent Articles
1.
Martinez-Pastor B, Silveira G, Clarke T, Chung D, Gu Y, Cosentino C, et al.
Cell Rep
. 2021 Dec;
37(13):110176.
PMID: 34965416
Repair of genetic damage is coordinated in the context of chromatin, so cells dynamically modulate accessibility at DNA breaks for the recruitment of DNA damage response (DDR) factors. The identification...
2.
Tam N, Chung D, Baldwin S, Simmons J, Xu L, Rainey J, et al.
J Mater Chem B
. 2020 Oct;
8(42):9718-9733.
PMID: 33015692
Cells reside in vivo within three dimensional environments in which they interact with extracellular matrices (ECMs) that play an integral role in maintaining tissue homeostasis and preventing tumour growth. Thus,...
3.
Attwood K, Salsman J, Chung D, Mathavarajah S, Van Iderstine C, Dellaire G
Biochem Cell Biol
. 2019 Nov;
98(3):314-326.
PMID: 31671275
Promyelocytic leukemia nuclear bodies (PML NBs) are nuclear subdomains that respond to genotoxic stress by increasing in number via changes in chromatin structure. However, the role of the PML protein...
4.
Chung D, Salsman J, Dellaire G
Cell Cycle
. 2019 May;
18(10):1135-1153.
PMID: 31057046
The cullin-RING E3 ubiquitin ligases (CRLs) play crucial roles in modulating the stability of proteins in the cell and are, in turn, regulated by post-translational modification by the ubiquitin-like (Ubl)...
5.
Baranes-Bachar K, Levy-Barda A, Oehler J, Reid D, Soria-Bretones I, Voss T, et al.
Mol Cell
. 2018 Mar;
69(5):866-878.e7.
PMID: 29499138
Double-strand breaks (DSBs) are critical DNA lesions that robustly activate the elaborate DNA damage response (DDR) network. We identified a critical player in DDR fine-tuning: the E3/E4 ubiquitin ligase UBE4A....
6.
Salsman J, Stathakis A, Parker E, Chung D, Anthes L, Koskowich K, et al.
Sci Rep
. 2017 Mar;
7:45038.
PMID: 28332630
The promyelocytic leukemia (PML) protein is an essential component of PML nuclear bodies (PML NBs) frequently lost in cancer. PML NBs coordinate chromosomal regions via modification of nuclear proteins that...
7.
Ramdzan Z, Ginjala V, Pinder J, Chung D, Donovan C, Kaur S, et al.
Oncotarget
. 2017 Feb;
8(12):19021-19038.
PMID: 28147323
Ionizing radiation generates a broad spectrum of oxidative DNA lesions, including oxidized base products, abasic sites, single-strand breaks and double-strand breaks. The CUX1 protein was recently shown to function as...
8.
Chung D, Dellaire G
Biomolecules
. 2015 Oct;
5(4):2388-416.
PMID: 26437438
The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result in a variety of diseases. Eukaryotic cells have developed...
9.
Yuki K, Eva M, Richer E, Chung D, Paquet M, Cellier M, et al.
PLoS One
. 2013 Feb;
8(2):e55331.
PMID: 23390527
Salmonella, a ubiquitous Gram-negative intracellular bacterium, is a food borne pathogen that infects a broad range of hosts. Infection with Salmonella Typhimurium in mice is a broadly recognized experimental model...