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Douglas R Smyth

Explore the profile of Douglas R Smyth including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 135
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Recent Articles
1.
Al-Ejeh F, Staudacher A, Smyth D, Darby J, Denoyer D, Tsopelas C, et al.
J Nucl Med . 2014 Mar; 55(5):772-9. PMID: 24676755
Unlabelled: Early identification of tumor responses to treatment is crucial for devising more effective and safer cancer treatments. No widely applicable, noninvasive method currently exists for specifically detecting tumor cell...
2.
de Vos D, Smyth D, Tiekink E
Met Based Drugs . 2008 May; 8(6):303-6. PMID: 18476010
The results of cytotoxicity trials against a panel of seven human cell lines for a series of triorganophosphinegold(I) 3- and 4-mercaptobenzoates are reported. While the new compounds show moderate to...
3.
Little T, Russo A, Meyer J, Horowitz M, Smyth D, Bellon M, et al.
Gastroenterology . 2007 Oct; 133(4):1124-31. PMID: 17919488
Background & Aims: The effects of fat on gastric emptying (GE), gut hormones, and energy intake are dependent on digestion to free fatty acids (FFAs). In animals, small intestinal oleic...
4.
Kang J, Cho H, Park C, Yun S, Kim J, Broker G, et al.
Inorg Chem . 2007 Sep; 46(20):8228-37. PMID: 17824604
The crystal structures of R3PAu[SC6H4C(=O)NH2-2], R = Et (1), Ph (2), and Cy (3) show linear coordination geometries for gold defined by sulfur and phosphorus atoms. Supramolecular aggregation via {...H-N-C=O}2...
5.
Smyth D
J Nucl Med Technol . 2006 Sep; 34(3):174-8. PMID: 16951287
Unlabelled: The purpose of this study was to validate a rapid quality control method for the lymphoscintigraphic tracer 99mTc-antimony trisulfide colloid (99mTc-ATC). Methods: ATC was labeled with 99mTc according to...
6.
Smyth D, Tsopelas C
Nucl Med Biol . 2005 Oct; 32(8):885-9. PMID: 16253814
(99m)Tc-aprotinin scintigraphy has been demonstrated to be a useful noninvasive imaging technique for amyloid deposits located in extraabdominal regions of patients. The aim of this study was to develop an...
7.
Sojan S, Smyth D, Tsopelas C, Mudge D, Collins P, Chatterton B
Nucl Med Commun . 2005 May; 26(6):535-9. PMID: 15891597
Objective: To confirm the pharmacokinetics and biodistribution of 99mTc aprotinin in normal volunteers and to determine the optimum time for scanning post-injection, prior to further investigations of 99mTc aprotinin as...
8.
Smyth D, Mrozkiewicz M, McGrath W, Listwan P, Kobe B
Protein Sci . 2003 Jun; 12(7):1313-22. PMID: 12824478
The fusion of a protein of interest to a large-affinity tag, such as the maltose-binding protein (MBP), thioredoxin (TRX), or glutathione-S-transferase (GST), can be advantageous in terms of increased expression,...