Douglas M McLaurin
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Explore the profile of Douglas M McLaurin including associated specialties, affiliations and a list of published articles.
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8
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32
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Recent Articles
1.
Lett K, McLaurin D, Tucker S, Hebert M
Front RNA Res
. 2024 Dec;
1.
PMID: 39703804
Cajal bodies (CBs) are subnuclear domains that contribute to the biogenesis of several different classes of ribonucleoproteins (RNPs) including small nuclear RNPs. Only some cell types contain abundant CBs, such...
2.
Tucker S, McLaurin D, Hebert M
J Cell Sci
. 2024 Dec;
137(23).
PMID: 39660502
Cajal bodies (CBs) are membraneless organelles whose mechanism of formation is still not fully understood. Many proteins contribute to the formation of CBs, including Nopp140 (NOLC1), WRAP53 and coilin. Coilin...
3.
McLaurin D, Tucker S, Hebert M
Biol Open
. 2023 Dec;
12(12).
PMID: 38050869
MicroRNAs (miRNAs) are a class of noncoding RNAs that regulate gene expression. An important step in miRNA biogenesis occurs when primary miRNAs are bound and cleaved by the microprocessor to...
4.
Logan M, Lett K, McLaurin D, Hebert M
Biol Open
. 2022 Jun;
11(7).
PMID: 35762874
The nuclear factor-Kappa B (NF-κB) pathway is a crucial mediator of inflammatory signaling. Aberrant activation of NF-κB is associated with several disorders including preeclampsia (PE). Many regulators of the NF-κB...
5.
Lett K, Logan M, McLaurin D, Hebert M
Mol Biol Cell
. 2021 Jul;
32(20):br4.
PMID: 34319763
MicroRNAs (miRNAs) are ∼22 nt small noncoding RNAs that control gene expression at the posttranscriptional level through translational inhibition and destabilization of their target mRNAs. The biogenesis of miRNAs involves...
6.
McLaurin D, Logan M, Lett K, Hebert M
Biol Open
. 2020 Oct;
9(10).
PMID: 33037012
The Cajal body (CB) is a subnuclear domain that participates in the biogenesis of many different types of ribonucleoproteins (RNPs), including small nuclear RNPs (snRNPs), small Cajal body-specific RNPs (scaRNPs)...
7.
Logan M, McLaurin D, Hebert M
Mol Biol Cell
. 2020 May;
31(15):1561-1569.
PMID: 32432989
Cajal bodies (CBs) are subnuclear domains involved in the formation of ribonucleoproteins (RNPs) including small nuclear RNPs (snRNPs). CBs associate with specific gene loci, which impacts expression and provides a...
8.
Burke M, McLaurin D, Logan M, Hebert M
Biol Open
. 2019 Mar;
8(3).
PMID: 30858166
The most common types of modification in human rRNA are pseudouridylation and 2'- ribose methylation. These modifications are performed by small nucleolar ribonucleoproteins (snoRNPs) which contain a guide RNA (snoRNA)...