Douglas E Faunce
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Explore the profile of Douglas E Faunce including associated specialties, affiliations and a list of published articles.
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24
Citations
981
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Recent Articles
1.
Brubaker A, Schneider D, Palmer J, Faunce D, Kovacs E
J Immunol Methods
. 2011 Sep;
373(1-2):161-6.
PMID: 21889511
Isolation of leukocytes from full-thickness excisional wounds has proven to be a difficult process that results in poor cell yield and holds significant limitations for functional assays. Given the increased...
2.
Schneider D, Palmer J, Tulley J, Kovacs E, Gamelli R, Faunce D
J Surg Res
. 2010 Nov;
171(1):361-73.
PMID: 21067780
We previously reported that in the absence of NKT cells, wound closure was accelerated in a murine excisional punch wound model. Here, we explored whether purposefully inhibiting NKT cell activation...
3.
Gomez C, Karavitis J, Palmer J, Faunce D, Ramirez L, Nomellini V, et al.
Mediators Inflamm
. 2010 Jul;
2010:475139.
PMID: 20671912
Here, we studied in vitro cytokine production by splenic macrophages obtained from young and aged BALB/c wild type (WT) and IL-6 knockout (IL-6 KO) mice. Relative to macrophages obtained from...
4.
Schneider D, Palmer J, Tulley J, Speicher J, Kovacs E, Gamelli R, et al.
J Surg Res
. 2010 Jan;
168(2):325-33.e1.
PMID: 20089261
Here, we report the novel observation that natural killer T (NKT) cells contribute to the cutaneous wound repair process. Using an excisional wound model in wild-type versus NKT cell-deficient mice,...
5.
Gomez C, Nomellini V, Faunce D, Kovacs E
Exp Gerontol
. 2008 Jul;
43(8):718-28.
PMID: 18586079
Advanced age is associated with defects in all of the cells of the innate immune system, including numbers, function, and early stages of activation. This review, presents the current state...
6.
Nomellini V, Faunce D, Gomez C, Kovacs E
J Leukoc Biol
. 2008 Mar;
83(6):1493-501.
PMID: 18319289
Burn patients over the age of 60 are at a greater risk for developing pulmonary complications than younger patients. The mechanisms for this, however, have yet to be elucidated. The...
7.
Tulley J, Palmer J, Gamelli R, Faunce D
Shock
. 2007 Aug;
29(2):269-77.
PMID: 17693934
Infection, sepsis, and multiple organ failure continue to be significant factors leading to morbidity and mortality after severe injury. Studies by our laboratory and others have identified injury-induced defects in...
8.
Schneider D, Glenn C, Faunce D
J Burn Care Res
. 2007 Apr;
28(3):365-79.
PMID: 17438501
The vast majority of clinical and basic science research on the immune consequences of burn injury and sepsis conducted during the last three decades has focused mainly on the roles...
9.
Fitzgerald D, Radek K, Chaar M, Faunce D, DiPietro L, Kovacs E
Alcohol Clin Exp Res
. 2007 Jan;
31(2):317-23.
PMID: 17250625
Background: Alcohol consumption is involved in over half of all trauma-related injuries. These patients are known to exhibit a higher incidence of mortality and morbidity following injury compared with patients...
10.
Palmer J, Tulley J, Kovacs E, Gamelli R, Taniguchi M, Faunce D
J Immunol
. 2006 Jun;
177(1):92-9.
PMID: 16785503
Overwhelming infection remains the leading cause of death from serious burn injury despite recent advances in the care of burn patients and a better understanding of immune and inflammatory consequences...