Douglas B Hornick
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Explore the profile of Douglas B Hornick including associated specialties, affiliations and a list of published articles.
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19
Citations
748
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Recent Articles
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Abou Alaiwa M, Hilkin B, Price M, Gansemer N, Rector M, Stroik M, et al.
bioRxiv
. 2024 Sep;
PMID: 39229081
Mutations in more than 50 different genes cause primary ciliary dyskinesia (PCD) by disrupting the activity of motile cilia that facilitate mucociliary transport (MCT). Knowledge of PCD has come from...
3.
Miller A, Harris L, Winthrop K, Cavanaugh J, Abou Alaiwa M, Hornick D, et al.
Open Forum Infect Dis
. 2024 Feb;
11(2):ofae024.
PMID: 38390464
Background: People with cystic fibrosis (CF) are at increased risk for bronchiectasis, and several reports suggest that CF carriers may also be at higher risk for developing bronchiectasis. The purpose...
4.
Beck M, Hornick D, Pena T, Singh S, Wright B
Pediatr Pulmonol
. 2023 Feb;
58(5):1569-1573.
PMID: 36807558
Background: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have shown beneficial effects on both forced expiratory volume in 1 s (FEV ) and frequency of pulmonary exacerbations in people with...
5.
Miller A, Harris L, Cavanaugh J, Abou Alaiwa M, Stoltz D, Hornick D, et al.
Clin Infect Dis
. 2022 Feb;
75(7):1115-1122.
PMID: 35142340
Background: People with cystic fibrosis (CF) routinely suffer from recurrent sinopulmonary infections. Such infections require frequent courses of antimicrobials and often involve multidrug-resistant organisms. The goal of this study was...
6.
Bouzek D, Abou Alaiwa M, Adam R, Pezzulo A, Reznikov L, Cook D, et al.
Am J Respir Crit Care Med
. 2021 Jun;
204(6):692-702.
PMID: 34170795
Although it is clear that cystic fibrosis (CF) airway disease begins at a very young age, the early and subsequent steps in disease pathogenesis and the relative contribution of infection,...
7.
Miller A, Arakkal A, Koeneman S, Cavanaugh J, Gerke A, Hornick D, et al.
BMJ Open
. 2021 Feb;
11(2):e045605.
PMID: 33602715
Objectives: Missed opportunities to diagnose tuberculosis are costly to patients and society. In this study, we (1) estimate the frequency and duration of diagnostic delays among patients with active pulmonary...
8.
Miller A, Comellas A, Hornick D, Stoltz D, Cavanaugh J, Gerke A, et al.
Proc Natl Acad Sci U S A
. 2019 Dec;
117(3):1621-1627.
PMID: 31882447
Autosomal recessive diseases, such as cystic fibrosis (CF), require inheritance of 2 mutated genes. However, some studies indicate that CF carriers are at increased risk for some conditions associated with...
9.
Polgreen P, Brown G, Hornick D, Ahmad F, London B, Stoltz D, et al.
Open Forum Infect Dis
. 2018 Nov;
5(11):ofy219.
PMID: 30397620
Background: Patients heterozygous for mutations in the () gene may be more susceptible to respiratory infections than the general population. Methods: We conducted a retrospective case-control study using health insurance...
10.
Goss C, Kaneko Y, Khuu L, Anderson G, Ravishankar S, Aitken M, et al.
Sci Transl Med
. 2018 Sep;
10(460).
PMID: 30257953
The lack of new antibiotics is among the most critical challenges facing medicine. The problem is particularly acute for Gram-negative bacteria. An unconventional antibiotic strategy is to target bacterial nutrition...