Dorothea J Heersema
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Explore the profile of Dorothea J Heersema including associated specialties, affiliations and a list of published articles.
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11
Citations
127
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Recent Articles
1.
Tan I, Modderman R, Stachurska A, Almeida R, de Vries R, Heersema D, et al.
Brain Commun
. 2024 Jul;
6(4):fcae209.
PMID: 38978729
Multiple sclerosis is a chronic demyelinating disease of the central nervous system. There is a need for new circulating biomarkers for multiple sclerosis, in particular, markers that differentiate multiple sclerosis...
2.
Reinhardt A, Rakers S, Heersema D, Beenakker E, Meilof J, Timmerman M, et al.
BMC Neurol
. 2024 Jun;
24(1):224.
PMID: 38943063
Background: Neuropsychological symptoms in the Cognitive, Energetic, Behavioural, and Affective (CEBA) domains are common in people with multiple sclerosis (PwMS) and can negatively affect societal participation. The current study aims...
3.
Horjus J, van Mourik-Banda T, Heerings M, Hakobjan M, De Witte W, Heersema D, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232761
Multiple sclerosis (MS) is a degenerative disease of the central nervous system in which auto-immunity-induced demyelination occurs. MS is thought to be caused by a complex interplay of environmental and...
4.
Wolkorte R, Heersema D, Zijdewind I
Neurorehabil Neural Repair
. 2015 Jul;
30(4):307-16.
PMID: 26156191
Background: Secondary-progressive multiple sclerosis (SPMS) patients have structural cortical damage resulting in increased compensatory cortical activity during (submaximal) performance. However, functional effects of changed cortical output are difficult to measure....
5.
Wolkorte R, Heersema D, Zijdewind I
Neurorehabil Neural Repair
. 2015 Jan;
29(8):796-802.
PMID: 25605633
Introduction: Fatigue is a common and debilitating symptom in patients with multiple sclerosis (MS). Self-reported levels of perceived fatigue are associated with both patient characteristics and clinical measures. Pilot analysis...
6.
Wolkorte R, Heersema D, Zijdewind I
Neurorehabil Neural Repair
. 2014 Oct;
29(5):424-35.
PMID: 25288582
Background: Multiple sclerosis (MS) can be accompanied by motor, cognitive, and sensory impairments. Additionally, MS patients often report fatigue as one of their most debilitating symptoms. It is, therefore, expected...
7.
Steen C, DHaeseleer M, Hoogduin J, Fierens Y, Cambron M, Mostert J, et al.
Mult Scler
. 2013 Feb;
19(10):1282-9.
PMID: 23428956
Background: Cerebral blood flow (CBF) is reduced in normal-appearing white matter (NAWM) of subjects with multiple sclerosis (MS), but the underlying mechanism is unknown. Objective: The objective of this article...
8.
Mostert J, Koch M, Heerings M, Heersema D, De Keyser J
CNS Neurosci Ther
. 2008 May;
14(2):153-64.
PMID: 18482027
The selective serotonin reuptake inhibitor (SSRI) fluoxetine, which is registered for a variety of psychiatric disorders, has been found to stimulate the cAMP-responsive element binding protein (CREB), increase the production...
9.
Koch M, Ramsaransing G, Fokkema M, Heersema D, De Keyser J
J Neurol Sci
. 2006 Mar;
244(1-2):123-6.
PMID: 16519904
Background: There is no good explanation why a proportion of patients with multiple sclerosis (MS) have a relatively benign form of the disease. An imbalance between saturated and unsaturated fatty...
10.
Koch M, Ramsaransing G, Arutjunyan A, Stepanov M, Teelken A, Heersema D, et al.
J Neurol
. 2005 Nov;
253(4):483-7.
PMID: 16283096
Background: The role of oxidative stress in patients with multiple sclerosis (MS) is poorly understood. Objective: To investigate oxidative stress in serum and peripheral blood leukocytes in patients with different...