Doris Herrmann
Overview
Explore the profile of Doris Herrmann including associated specialties, affiliations and a list of published articles.
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49
Citations
941
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Recent Articles
1.
Ruan D, Xuan Y, Tam T, Li Z, Wang X, Xu S, et al.
Nat Protoc
. 2024 Mar;
19(6):1710-1749.
PMID: 38509352
Pigs share anatomical and physiological traits with humans and can serve as a large-animal model for translational medicine. Bona fide porcine pluripotent stem cells (PSCs) could facilitate testing cell and...
2.
Sollner J, Sake H, Frenzel A, Lechler R, Herrmann D, Fuchs W, et al.
PLoS One
. 2022 Dec;
17(12):e0279123.
PMID: 36584049
Due to its close resemblance, the domesticated pig has proven to be a diverse animal model for biomedical research and genome editing tools have contributed to developing porcine models for...
3.
Gutierrez-Anez J, Henning H, Lucas-Hahn A, Baulain U, Aldag P, Sieg B, et al.
PLoS One
. 2021 Sep;
16(9):e0256701.
PMID: 34473747
The developmental competence of male and female gametes is frequently reduced under in vitro conditions, mainly due to oxidative stress during handling. The amino-acid derived hormone melatonin has emerged as...
4.
Kruger L, Nowak-Imialek M, Kristiansen Y, Herrmann D, Petersen B, Denner J
Virus Res
. 2021 Jan;
294:198295.
PMID: 33422555
Expanded potential stem cells (EPSCs) have been recently derived from porcine preimplantation embryos (Gao et al., 2019). These cells were shown to express key pluripotency genes, to be genetically stable...
5.
Nowak-Imialek M, Wunderlich S, Herrmann D, Breitschuh-Leibling S, Gohring G, Petersen B, et al.
Cell Reprogram
. 2020 May;
22(3):118-133.
PMID: 32429746
Chimeric pigs harboring organs derived from human stem cells are promising for patient-specific regenerative therapies. Induced pluripotent stem cells (iPSCs) can contribute to all cell types of the fetus, including...
6.
Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, et al.
Nat Cell Biol
. 2019 Jun;
21(6):687-699.
PMID: 31160711
We recently derived mouse expanded potential stem cells (EPSCs) from individual blastomeres by inhibiting the critical molecular pathways that predispose their differentiation. EPSCs had enriched molecular signatures of blastomeres and...
7.
Mall E, Herrmann D, Niemann H
Stem Cell Res
. 2017 Oct;
25:50-60.
PMID: 29080444
Foxg1 is a transcription factor critical for the development of the mammalian telencephalon. Foxg1 controls the proliferation of dorsal telencephalon progenitors and the specification of the ventral telencephalon. Homozygous knockout...
8.
Petersen B, Frenzel A, Lucas-Hahn A, Herrmann D, Hassel P, Klein S, et al.
Xenotransplantation
. 2016 Sep;
23(5):338-46.
PMID: 27610605
Background: Xenotransplantation is considered to be a promising solution to the growing demand for suitable donor organs for transplantation. Despite tremendous progress in the generation of pigs with multiple genetic...
9.
Mattern F, Herrmann D, Heinzmann J, Hadeler K, Bernal-Ulloa S, Haaf T, et al.
Mol Reprod Dev
. 2016 Aug;
83(9):802-814.
PMID: 27567027
Epigenetic changes are critical for the acquisition of developmental potential by oocytes and embryos, yet these changes may be sensitive to maternal ageing. Here, we investigated the impact of maternal...
10.
Ahrens H, Petersen B, Ramackers W, Petkov S, Herrmann D, Hauschild-Quintern J, et al.
Transplant Direct
. 2016 Aug;
1(6):e23.
PMID: 27500225
Unlabelled: Multiple modifications of the porcine genome are required to prevent rejection after pig-to-primate xenotransplantation. Here, we produced pigs with a knockout of the α1,3-galactosyltransferase gene (GGTA1-KO) combined with transgenic...