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Doris A Chatfield

Explore the profile of Doris A Chatfield including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 819
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Recent Articles
1.
Rua C, Raman B, Rodgers C, Newcombe V, Manktelow A, Chatfield D, et al.
Brain . 2024 Oct; 147(12):4121-4130. PMID: 39375207
Post-mortem studies have shown that patients dying from severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection frequently have pathological changes in their CNS, particularly in the brainstem. Many of these changes...
2.
Tsvetanov K, Spindler L, Stamatakis E, Newcombe V, Lupson V, Chatfield D, et al.
Neuroimage Clin . 2022 Dec; 36:103253. PMID: 36451358
Human coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has multiple neurological consequences, but its long-term effect on brain health is still uncertain. The cerebrovascular consequences...
3.
Needham E, Ren A, Digby R, Norton E, Ebrahimi S, Outtrim J, et al.
Brain . 2022 Sep; 145(11):4097-4107. PMID: 36065116
COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19 severity. The true...
4.
Hampshire A, Chatfield D, MPhil A, Jolly A, Trender W, Hellyer P, et al.
EClinicalMedicine . 2022 May; 47:101417. PMID: 35505938
Background: Preliminary evidence has highlighted a possible association between severe COVID-19 and persistent cognitive deficits. Further research is required to confirm this association, determine whether cognitive deficits relate to clinical...
5.
Newcombe V, Ashton N, Posti J, Glocker B, Manktelow A, Chatfield D, et al.
Brain . 2022 Apr; 145(6):2064-2076. PMID: 35377407
There is substantial interest in the potential for traumatic brain injury to result in progressive neurological deterioration. While blood biomarkers such as glial fibrillary acid protein (GFAP) and neurofilament light...
6.
Chatfield D, Lee S, Cowley J, Kitzinger C, Kitzinger J, Menon D
Nurs Crit Care . 2017 Mar; 23(2):82-87. PMID: 28247553
Background: This research explores the current and potential future role of independent mental capacity advocates (IMCAs) in critical care. The Mental Capacity Act (MCA) of 2005 introduced IMCAs as advocates...
7.
Newcombe V, Outtrim J, Chatfield D, Manktelow A, Hutchinson P, Coles J, et al.
Brain . 2011 Feb; 134(Pt 3):759-68. PMID: 21310727
Cognitive dysfunction is a devastating consequence of traumatic brain injury that affects the majority of those who survive with moderate-to-severe injury, and many patients with mild head injury. Disruption of...
8.
Chatfield D, Brahmbhatt D, Sharp T, Perkes I, Outrim J, Menon D
Neurocrit Care . 2010 Jul; 14(1):55-60. PMID: 20652766
Background: Endothelin-1 (ET-1) is a potent vasoconstrictor and is thought to be responsible for secondary ischemia and vasogenic edema after traumatic brain injury (TBI). Both CSF and plasma concentrations have...
9.
Newcombe V, Williams G, Nortje J, Bradley P, Chatfield D, Outtrim J, et al.
Acta Neurochir Suppl . 2009 Apr; 102:247-51. PMID: 19388324
Background: Cerebral edema is a common sequelum post traumatic brain injury (TBI). Quantification of the apparent diffusion coefficient (ADC) using diffusion tensor imaging (DTI) may help to characterize the pathophysiology...
10.
Coles J, Cunningham A, Salvador R, Chatfield D, Carpenter A, Pickard J, et al.
J Cereb Blood Flow Metab . 2009 Mar; 29(5):965-75. PMID: 19293825
We defined lesion and structurally normal regions using magnetic resonance imaging at follow-up in patients recovering from head injury. Early metabolic characteristics in these regions of interest (ROIs) were compared...