Dorian V Ziegler
Overview
Explore the profile of Dorian V Ziegler including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
581
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Recent Articles
1.
Ziegler D, Parashar K, Leal-Esteban L, Lopez-Alcala J, Castro W, Zanou N, et al.
Nat Commun
. 2025 Jan;
16(1):541.
PMID: 39788939
The energetic demands of proliferating cells during tumorigenesis require close coordination between the cell cycle and metabolism. While CDK4 is known for its role in cell proliferation, its metabolic function...
2.
Grepper D, Tabasso C, Zanou N, Aguettaz A, Castro-Sepulveda M, Ziegler D, et al.
iScience
. 2024 Aug;
27(8):110510.
PMID: 39175772
The physical connection between mitochondria and endoplasmic reticulum (ER) is an essential signaling hub to ensure organelle and cellular functions. In skeletal muscle, ER-mitochondria calcium (Ca) signaling is crucial to...
3.
Huber K, Giralt A, Dreos R, Michenthaler H, Geller S, Barquissau V, et al.
Biochim Biophys Acta Mol Cell Res
. 2024 Apr;
1871(5):119721.
PMID: 38580088
Metabolic reprogramming is considered as a hallmark of cancer and is clinically exploited as a novel target for therapy. The E2F transcription factor-1 (E2F1) regulates various cellular processes, including proliferative...
4.
Ziegler D, Czarnecka-Herok J, Vernier M, Scholtes C, Camprubi C, Huna A, et al.
NPJ Aging
. 2024 Jan;
10(1):5.
PMID: 38216569
Cellular senescence is a cell program induced by various stresses that leads to a stable proliferation arrest and to a senescence-associated secretory phenotype. Accumulation of senescent cells during age-related diseases...
5.
Ziegler D, Parashar K, Fajas L
Semin Cancer Biol
. 2023 Dec;
98:51-63.
PMID: 38135020
CDK4, along with its regulatory subunit, cyclin D, drives the transition from G1 to S phase, during which DNA replication and metabolic activation occur. In this canonical pathway, CDK4 is...
6.
Jaber S, Warnier M, Leers C, Vernier M, Goehrig D, Medard J, et al.
Mol Biomed
. 2023 Feb;
4(1):4.
PMID: 36739330
Pancreatic cancer is one of the deadliest cancers owing to its late diagnosis and of the strong resistance to available treatments. Despite a better understanding of the disease in the...
7.
Ziegler D, Huber K, Fajas L
Cancers (Basel)
. 2022 Jan;
14(1).
PMID: 35008317
In the past decade, cell cycle regulators have extended their canonical role in cell cycle progression to the regulation of various cellular processes, including cellular metabolism. The regulation of metabolism...
8.
Ziegler D, Martin N, Bernard D
Commun Biol
. 2021 Nov;
4(1):1323.
PMID: 34819602
Membrane contact sites emerged in the last decade as key players in the integration, regulation and transmission of many signals within cells, with critical impact in multiple pathophysiological contexts. Numerous...
9.
Ziegler D, Vindrieux D, Goehrig D, Jaber S, Collin G, Griveau A, et al.
Nat Commun
. 2021 Feb;
12(1):720.
PMID: 33526781
Cellular senescence is induced by stresses and results in a stable proliferation arrest accompanied by a pro-inflammatory secretome. Senescent cells accumulate during aging, promoting various age-related pathologies and limiting lifespan....
10.
Martin N, Ziegler D, Parent R, Bernard D
Hepatology
. 2020 Sep;
73(2):853-855.
PMID: 32931043
No abstract available.