Donna K Slonim
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Explore the profile of Donna K Slonim including associated specialties, affiliations and a list of published articles.
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42
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1134
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Recent Articles
1.
Draper I, Huang W, Pande S, Zou A, Calamaras T, Choe R, et al.
FEBS Lett
. 2024 Sep;
598(21):2670-2682.
PMID: 39300280
Heart failure (HF) is highly prevalent. Mechanisms underlying HF remain incompletely understood. Splicing factors (SF), which control pre-mRNA alternative splicing, regulate cardiac structure and function. This study investigated regulation of...
2.
Zitnik M, Li M, Wells A, Glass K, Morselli Gysi D, Krishnan A, et al.
Bioinform Adv
. 2024 Aug;
4(1):vbae099.
PMID: 39143982
Summary: Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseases across biological systems and scales....
3.
Shook L, Batorsky R, De Guzman R, McCrea L, Brigida S, Horng J, et al.
J Neuroinflammation
. 2024 Jun;
21(1):163.
PMID: 38918792
Background: The SARS-CoV-2 virus activates maternal and placental immune responses. Such activation in the setting of other infections during pregnancy is known to impact fetal brain development. The effects of...
4.
Batorsky R, Ceasrine A, Shook L, Kislal S, Bordt E, Devlin B, et al.
Cell Rep
. 2024 Jun;
43(6):114326.
PMID: 38848212
Maternal immune activation is associated with adverse offspring neurodevelopmental outcomes, many mediated by in utero microglial programming. As microglia remain inaccessible throughout development, identification of noninvasive biomarkers reflecting fetal brain...
5.
Batorsky R, Ceasrine A, Shook L, Kislal S, Bordt E, Devlin B, et al.
bioRxiv
. 2024 Jan;
PMID: 38187648
Maternal immune activation is associated with adverse offspring neurodevelopmental outcomes, many mediated by in utero microglial programming. As microglia remain inaccessible throughout development, identification of noninvasive biomarkers reflecting fetal brain...
6.
Sapashnik D, Newman R, Pietras C, Zhou D, Devkota K, Qu F, et al.
PLoS One
. 2023 Feb;
18(2):e0278289.
PMID: 36795645
Drug repositioning allows expedited discovery of new applications for existing compounds, but re-screening vast compound libraries is often prohibitively expensive. "Connectivity mapping" is a process that links drugs to diseases...
7.
Alexander M, Hightower R, Reid A, Bennett A, Iyer L, Slonim D, et al.
Muscle Nerve
. 2021 Mar;
63(6):928-940.
PMID: 33651408
Introduction: RNA-binding proteins (RBPs) play an important role in skeletal muscle development and disease by regulating RNA splicing. In myotonic dystrophy type 1 (DM1), the RBP MBNL1 (muscleblind-like) is sequestered...
8.
El-Mabrouk N, Slonim D
Bioinformatics
. 2020 Jul;
36(Suppl_1):i1-i2.
PMID: 32657353
No abstract available.
9.
Pietras C, Power L, Slonim D
Pac Symp Biocomput
. 2019 Dec;
25:683-694.
PMID: 31797638
Dynamic processes are inherently important in disease, and identifying disease-related disruptions of normal dynamic processes can provide information about individual patients. We have previously characterized individuals' disease states via pathway-based...
10.
Toorie A, Vassoler F, Qu F, Schonhoff C, Bradburn S, Murgatroyd C, et al.
Addict Biol
. 2019 Nov;
26(1):e12856.
PMID: 31782234
Worldwide consumption of opioids remains at historic levels. Preclinical studies report intergenerational effects on the endogenous opioid system of future progeny following preconception morphine exposure. Given the role of endogenous...