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Dongxue Xu

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Articles 29
Citations 1130
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Recent Articles
1.
Pang J, Xu D, Zhang X, Qu J, Jiang J, Suo J, et al.
Free Radic Biol Med . 2025 Feb; 232:244-259. PMID: 39986488
Acute kidney injury (AKI) triggers renal structural and functional abnormalities through inflammatory and fibrotic signaling pathways, ultimately progressing to chronic kidney disease (CKD). The mechanisms underlying AKI-to-CKD transition are complex,...
2.
Xing Y, Wang M, Zhang F, Xin T, Wang X, Chen R, et al.
Nat Commun . 2025 Jan; 16(1):985. PMID: 39856099
Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. Here, we describe an unrecognized role for the lysosome, showing that it finely...
3.
Liu J, Chen Y, Song Y, Xu D, Gu Y, Wang J, et al.
Environ Pollut . 2024 Jun; 357:124394. PMID: 38901819
Microplastics are ubiquitous pollutants in the global marine environment. However, few studies have adequately explored the different toxic mechanisms of microplastics (MPs) and nanoplastics (NPs) in aquatic organisms. The sea...
4.
Xu D, Jiang J, Liu Y, Pang J, Suo J, Li Y, et al.
Am J Physiol Cell Physiol . 2024 Mar; 326(5):C1353-C1366. PMID: 38497110
The tissue inhibitor of metalloproteinases 2 (TIMP2) has emerged as a promising biomarker for predicting the risk of sepsis-associated acute kidney injury (SA-AKI). However, its exact role in SA-AKI and...
5.
Song Y, Sun M, Ma F, Xu D, Mu G, Jiao Y, et al.
Probiotics Antimicrob Proteins . 2023 Jan; 16(2):321-333. PMID: 36715883
In this study, the strain Lactiplantibacillus plantarum DLPT4 was investigated for the immunostimulatory activity in cyclophosphamide (CTX)-induced immunosuppressed BALB/c mice. L. plantarum DLPT4 was administered to BALB/c mice by oral...
6.
Gu Y, Xu D, Liu J, Chen Y, Wang J, Song Y, et al.
Environ Pollut . 2023 Jan; 319:121015. PMID: 36610653
Micro/nano-plastics (M/NPs) are emerging contaminants in aquatic environment, however, little knowledge regarding the adverse effects of functionalized NPs has been documented so far. This study investigated the accumulation of different...
7.
Li Y, Xu D, Zhang J, Suo J, Jiang J, Qian Y, et al.
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue . 2022 Jun; 34(4):394-399. PMID: 35692205
Objective: To explore the effect of Toll-like receptor 9 (TLR9) signaling pathway activation on the transcriptome in the renal tubular cells. Methods: Mouse primary renal tubular epithelial cells were extracted...
8.
Jiang N, Huang R, Zhang J, Xu D, Li T, Sun Z, et al.
FASEB J . 2022 Feb; 36(4):e22228. PMID: 35218571
Tissue inhibitor of metalloproteinase 2 (TIMP2) has been recognized as an important biomarker for predicting acute kidney injury (AKI) because of its involvement in the process of inflammation and apoptosis...
9.
Xu D, Fang H, Liu J, Chen Y, Gu Y, Sun G, et al.
Sci Total Environ . 2022 Jan; 820:153168. PMID: 35051475
Heat stress poses an increasing threat for the marine invertebrate Apostichopus japonicus. Histone lysine acetylation is a central chromatin modification for epigenetic regulation of gene expression during stress response. In...
10.
Xu D, Liu J, Gu Y, Chen Y, Zhao C, Sun G, et al.
J Agric Food Chem . 2021 Dec; 69(49):14802-14809. PMID: 34852201
Compound-specific stable isotope analysis of individual amino acids (AAs) has been widely used in studies on food webs, resource tracing, and biochemical cycling. In the present study, juvenile sea cucumbers...