Dona L Wong
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Explore the profile of Dona L Wong including associated specialties, affiliations and a list of published articles.
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13
Citations
132
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Recent Articles
1.
Tai T, Wong-Faull D, Claycomb R, Wong D
Brain Res
. 2010 Jul;
1353:14-27.
PMID: 20654592
Hypoxia is shown to regulate the stress hormone epinephrine through its biosynthesis by phenylethanolamine N-methyltransferase (PNMT) via PNMT gene activation and transcription factors Egr-1 and Sp1 in adrenal medulla-derived PC12...
2.
Tai T, Wong-Faull D, Claycomb R, Wong D
J Neurochem
. 2009 Feb;
109(2):513-24.
PMID: 19220706
Sustaining epinephrine-elicited behavioral and physiological responses during stress requires replenishment of epinephrine stores. Egr-1 and Sp1 contribute by stimulating the gene encoding the epinephrine-synthesizing enzyme, phenylethanolamine N-methyltransferase (PNMT), as shown...
3.
Wong D, Tai T, Wong-Faull D, Claycomb R, Kvetnansky R
Ann N Y Acad Sci
. 2009 Jan;
1148:249-56.
PMID: 19120117
Stress effects on adrenergic responses in rats were examined in adrenal medulla, the primary source of circulating epinephrine (Epi). Irrespective of duration, immobilization (IMMO) increased adrenal corticosterone to the same...
4.
Tai T, Claycomb R, Siddall B, Bell R, Kvetnansky R, Wong D
J Neurochem
. 2007 Mar;
101(4):1108-18.
PMID: 17394532
Immobilization (IMMO) stress was used to examine how stress alters the stress hormone epinephrine (EPI) in the adrenal medulla in vivo. In rats subjected to IMMO for 30 or 120...
5.
Huynh T, Pacak K, Wong D, Linehan W, Goldstein D, Elkahloun A, et al.
Ann N Y Acad Sci
. 2006 Nov;
1073:241-52.
PMID: 17102092
Pheochromocytomas in multiple endocrine neoplasia type 2 (MEN-2) express phenylethanolamine N-methyltransferase (PNMT), the enzyme that catalyzes conversion of norepinephrine to epinephrine, whereas those in von Hippel-Lindau (VHL) syndrome do not....
6.
Tai T, Wong-Faull D, Claycomb R, Wong D
Mol Pharmacol
. 2006 Aug;
70(5):1792-801.
PMID: 16926281
The mechanism by which nerve growth factor (NGF) regulates adrenergic expression was examined in PC-12 cells transfected with a rat phenylethanolamine N-methyl-transferase (PNMT) promoter-luciferase reporter gene construct pGL3RP893. NGF treatment...
7.
Wong D, Tai T, Wong-Faull D, Claycomb R, Kvetnansky R
Ann N Y Acad Sci
. 2004 Jul;
1018:387-97.
PMID: 15240394
Cortisol and epinephrine released in response to stress are replenished via activation of the hypothalamic-pituitary-adrenal (HPA or stress) axis. Immobilization (IMMO) stress in rats stimulates epinephrine production in part via...
8.
Her S, Claycomb R, Tai T, Wong D
Mol Pharmacol
. 2003 Oct;
64(5):1180-8.
PMID: 14573768
The rat phenylethanolamine N-methyltransferase (PNMT) gene promoter contains 1-base pair (bp) overlapping consensus sequences for Sp1 and MAZ transcription factors at -48 and -38 bp, respectively. Gel mobility assays using...
9.
Wong D
Endocr Pathol
. 2003 May;
14(1):25-36.
PMID: 12746560
The adrenal gland is the body's primary source for epinephrine production and release, and the chromaffin cells that comprise the adrenal medulla possess all of the catecholamine biosynthetic machinery, including...
10.
Tai T, Wong D
J Neurochem
. 2003 Apr;
85(3):816-29.
PMID: 12694408
The protein kinase A (PKA) and protein kinase C (PKC) signaling pathways appear to interact in regulating phenylethanolamine N-methyltransferase (PNMT) promoter-driven gene transcription in PC12 cells. Forskolin treatment of cells...