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Don B Gammon

Explore the profile of Don B Gammon including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Rex E, Seo D, Embry A, Arulanandam R, Spinelli M, Diallo J, et al.
bioRxiv . 2025 Mar; PMID: 40060670
We recently identified the FACT-ETS-1 Antiviral Response (FEAR) pathway as an interferon-independent innate immune response that restricts DNA virus replication and is countered by poxvirus-encoded A51R proteins (Rex , 2024,...
2.
Embry A, Schad D, Rex E, Alto N, Gammon D
bioRxiv . 2024 Nov; PMID: 39574573
Arboviruses are a group of arthropod-transmitted viruses that pose a significant threat to public health. Identifying host factors that inhibit arbovirus infection is critical for the development of strategies to...
3.
Seo D, Yue Y, Yamazaki S, Verhey K, Gammon D
Int J Mol Sci . 2024 Jul; 25(14). PMID: 39063067
Microtubule (MT)-dependent transport is a critical means of intracellular movement of cellular cargo by kinesin and dynein motors. MT-dependent transport is tightly regulated by cellular MT-associated proteins (MAPs) that directly...
4.
Embry A, Baggett N, Heisler D, White A, de Jong M, Kocsis B, et al.
PLoS Pathog . 2024 May; 20(5):e1012010. PMID: 38753575
Arboviruses are a diverse group of insect-transmitted pathogens that pose global public health challenges. Identifying evolutionarily conserved host factors that combat arbovirus replication in disparate eukaryotic hosts is important as...
5.
Embry A, Gammon D
Annu Rev Virol . 2024 Apr; 11(1):193-213. PMID: 38631917
Even if a virus successfully binds to a cell, defects in any of the downstream steps of the viral life cycle can preclude the production of infectious virus particles. Such...
6.
Rex E, Seo D, Chappidi S, Pinkham C, Brito Oliveira S, Embry A, et al.
Nat Microbiol . 2024 Mar; 9(4):988-1006. PMID: 38538832
The human facilitates chromatin transcription (FACT) complex is a chromatin remodeller composed of human suppressor of Ty 16 homologue (hSpt16) and structure-specific recognition protein-1 subunits that regulates cellular gene expression....
7.
Seo D, Brito Oliveira S, Rex E, Ye X, Rice L, Guimaraes da Fonseca F, et al.
Cell Rep . 2024 Mar; 43(3):113882. PMID: 38457341
Numerous viruses alter host microtubule (MT) networks during infection, but how and why they induce these changes is unclear in many cases. We show that the vaccinia virus (VV)-encoded A51R...
8.
Embry A, Baggett N, Heisler D, White A, de Jong M, Kocsis B, et al.
bioRxiv . 2024 Feb; PMID: 38352400
Arboviruses are a diverse group of insect-transmitted pathogens that pose global public health challenges. Identifying evolutionarily conserved host factors that combat arbovirus replication in disparate eukaryotic hosts is important as...
9.
Rex E, Seo D, Chappidi S, Pinkham C, Brito Oliveira S, Embry A, et al.
bioRxiv . 2023 Feb; PMID: 36798356
The FACT complex is an ancient chromatin remodeling factor comprised of Spt16 and SSRP1 subunits that regulates specific eukaryotic gene expression programs. However, whether FACT regulates host immune responses to...
10.
Reus J, Rex E, Gammon D
Pathogens . 2022 Sep; 11(9). PMID: 36145493
The Nuclear Factor-kappa B (NF-κB) family of transcription factors regulates key host inflammatory and antiviral gene expression programs, and thus, is often activated during viral infection through the action of...