Dominic Holland
Overview
Explore the profile of Dominic Holland including associated specialties, affiliations and a list of published articles.
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82
Citations
5932
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Recent Articles
1.
Frei O, Hindley G, Shadrin A, van der Meer D, Akdeniz B, Hagen E, et al.
Nat Genet
. 2024 Jun;
56(6):1310-1318.
PMID: 38831010
While genome-wide association studies are increasingly successful in discovering genomic loci associated with complex human traits and disorders, the biological interpretation of these findings remains challenging. Here we developed the...
2.
Parekh P, Fan C, Frei O, Palmer C, Smith D, Makowski C, et al.
Hum Brain Mapp
. 2024 Feb;
45(2):e26579.
PMID: 38339910
The linear mixed-effects model (LME) is a versatile approach to account for dependence among observations. Many large-scale neuroimaging datasets with complex designs have increased the need for LME; however LME...
3.
Reas E, Shadrin A, Frei O, Motazedi E, McEvoy L, Bahrami S, et al.
Alzheimers Dement
. 2023 May;
19(11):5151-5158.
PMID: 37132098
Introduction: There is a pressing need for non-invasive, cost-effective tools for early detection of Alzheimer's disease (AD). Methods: Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), Cox proportional models...
4.
Wightman D, Jansen I, Savage J, Shadrin A, Bahrami S, Holland D, et al.
Nat Genet
. 2022 Jun;
54(7):1062.
PMID: 35726068
No abstract available.
5.
Wightman D, Jansen I, Savage J, Shadrin A, Bahrami S, Holland D, et al.
Nat Genet
. 2021 Nov;
53(12):1722.
PMID: 34773122
No abstract available.
6.
Shadrin A, Kaufmann T, van der Meer D, Palmer C, Makowski C, Loughnan R, et al.
Neuroimage
. 2021 Sep;
244:118603.
PMID: 34560273
Brain morphology has been shown to be highly heritable, yet only a small portion of the heritability is explained by the genetic variants discovered so far. Here we extended the...
7.
Wightman D, Jansen I, Savage J, Shadrin A, Bahrami S, Holland D, et al.
Nat Genet
. 2021 Sep;
53(9):1276-1282.
PMID: 34493870
Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts for 50-70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer's disease have been identified....
8.
Holland D, Frei O, Desikan R, Fan C, Shadrin A, Smeland O, et al.
Genetics
. 2021 Jun;
218(2).
PMID: 34167151
No abstract available.
9.
Holland D, Frei O, Desikan R, Fan C, Shadrin A, Smeland O, et al.
Genetics
. 2021 Mar;
217(3).
PMID: 33789345
We propose an extended Gaussian mixture model for the distribution of causal effects of common single nucleotide polymorphisms (SNPs) for human complex phenotypes that depends on linkage disequilibrium (LD) and...
10.
Rodriguez-Soto A, Fang L, Holland D, Zou J, Park H, Keenan K, et al.
J Magn Reson Imaging
. 2021 Mar;
53(5):1581-1591.
PMID: 33644939
Background: Diffusion-weighted (DW) echo-planar imaging (EPI) is prone to geometric distortions due to B inhomogeneities. Both prospective and retrospective approaches have been developed to decrease and correct such distortions. Purpose:...