Diwakar Santhakumar
Overview
Explore the profile of Diwakar Santhakumar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
271
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Santhakumar D, Rohaim M, Munir M
Vaccines (Basel)
. 2019 Nov;
7(4).
PMID: 31717701
Interferons (IFNs) play central roles in establishing innate immunity and mediating adaptive immunity against multiple pathogens. Three known types of IFNs identify their cognate receptors, initiate cascades of signalling events...
2.
Arslan M, Yang X, Santhakumar D, Liu X, Hu X, Munir M, et al.
Genes (Basel)
. 2019 Feb;
10(2).
PMID: 30769908
Interferons (IFNs) are pleiotropic cytokines that establish a first line of defense against viral infections in vertebrates. Several types of IFN have been identified; however, limited information is available in...
3.
Rohaim M, Santhakumar D, El Naggar R, Iqbal M, Hussein H, Munir M
Front Immunol
. 2018 Oct;
9:2025.
PMID: 30271403
Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This antiviral potential of innate immunity is mainly attributed to...
4.
Santhakumar D, Rohaim M, Hussein H, Hawes P, Ferreira H, Behboudi S, et al.
Sci Rep
. 2018 May;
8(1):6794.
PMID: 29717152
The intracellular actions of interferon (IFN)-regulated proteins, including IFN-induced proteins with tetratricopeptide repeats (IFITs), attribute a major component of the protective antiviral host defense. Here we applied genomics approaches to...
5.
Santhakumar D, Iqbal M, Nair V, Munir M
Sci Rep
. 2017 Jun;
7(1):2719.
PMID: 28578423
Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I IFNs are identified, however, only limited data...
6.
Santhakumar D, Rubbenstroth D, Martinez-Sobrido L, Munir M
Front Immunol
. 2017 Feb;
8:49.
PMID: 28197148
Interferon (IFN) responses, mediated by a myriad of IFN-stimulated genes (ISGs), are the most profound innate immune responses against viruses. Cumulatively, these IFN effectors establish a multilayered antiviral state to...
7.
Infectivity of wild bird-origin avian paramyxovirus serotype 1 and vaccine effectiveness in chickens
Shabbir M, Akhtar S, Tang Y, Yaqub T, Ahmad A, Mustafa G, et al.
J Gen Virol
. 2016 Oct;
97(12):3161-3173.
PMID: 27692048
Newcastle disease virus, a prototype avian paramyxovirus serotype 1 (APMV-1), causes economically devastating disease in avian species around the world. Newcastle disease is enzootic in Pakistan and recurrent outbreaks are...
8.
Libri V, Helwak A, Miesen P, Santhakumar D, Borger J, Kudla G, et al.
Proc Natl Acad Sci U S A
. 2011 Dec;
109(1):279-84.
PMID: 22184245
Individual microRNAs (miRNAs) are rapidly down-regulated during conditions of cellular activation and infection, but factors mediating miRNA turnover are poorly understood. Infection of mouse cells with murine cytomegalovirus (MCMV) induces...
9.
Santhakumar D, Forster T, Laqtom N, Fragkoudis R, Dickinson P, Abreu-Goodger C, et al.
Proc Natl Acad Sci U S A
. 2010 Jul;
107(31):13830-5.
PMID: 20643939
Although the functional parameters of microRNAs (miRNAs) have been explored in some depth, the roles of these molecules in viral infections remain elusive. Here we report a general method for...