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Dirk Weisensee

Explore the profile of Dirk Weisensee including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 195
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Recent Articles
1.
Mathis C, Gebel S, Poussin C, Belcastro V, Sewer A, Weisensee D, et al.
Bioinform Biol Insights . 2015 Mar; 9:19-35. PMID: 25788831
To establish a relevant in vitro model for systems toxicology-based mechanistic assessment of environmental stressors such as cigarette smoke (CS), we exposed human organotypic bronchial epithelial tissue cultures at the...
2.
Rovida C, Alepee N, Api A, Basketter D, Bois F, Caloni F, et al.
ALTEX . 2014 Nov; 32(1):25-40. PMID: 25413849
Integrated testing strategies (ITS), as opposed to single definitive tests or fixed batteries of tests, are expected to efficiently combine different information sources in a quantifiable fashion to satisfy an...
3.
Westra J, Schlage W, Hengstermann A, Gebel S, Mathis C, Thomson T, et al.
Bioinform Biol Insights . 2013 Jul; 7:167-92. PMID: 23843693
Exposure to environmental stressors such as cigarette smoke (CS) elicits a variety of biological responses in humans, including the induction of inflammatory responses. These responses are especially pronounced in the...
4.
Weisensee D, Poth A, Roemer E, Conroy L, Schlage W
Altern Lab Anim . 2013 Jun; 41(2):181-9. PMID: 23781935
In vitro cell transformation assays detect transformed cells that have acquired the distinct characteristics of malignant cells and thus model one stage of in vivo carcinogenesis. These assays have been...
5.
Roemer E, Lammerich H, Conroy L, Weisensee D
Toxicol Lett . 2013 Apr; 219(3):248-53. PMID: 23558295
Inhibition of gap-junctional intercellular communication (GJIC) via exposure to various toxic substances has been implicated in tumor promotion. In the present study, cigarette smoke total particulate matter (TPM), a known...
6.
Mathis C, Poussin C, Weisensee D, Gebel S, Hengstermann A, Sewer A, et al.
Am J Physiol Lung Cell Mol Physiol . 2013 Jan; 304(7):L489-503. PMID: 23355383
Organotypic culture of human primary bronchial epithelial cells is a useful in vitro system to study normal biological processes and lung disease mechanisms, to develop new therapies, and to assess...
7.
Martin F, Thomson T, Sewer A, Drubin D, Mathis C, Weisensee D, et al.
BMC Syst Biol . 2012 Jun; 6:54. PMID: 22651900
Background: High-throughput measurement technologies produce data sets that have the potential to elucidate the biological impact of disease, drug treatment, and environmental agents on humans. The scientific community faces an...