Dirk-Peter Herten
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Explore the profile of Dirk-Peter Herten including associated specialties, affiliations and a list of published articles.
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51
Citations
554
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Recent Articles
1.
Bryan 4th J, Bryan J, Tashev S, Fazel M, Scheckenbach M, Tinnefeld P, et al.
bioRxiv
. 2025 Feb;
PMID: 39975252
The study of binding kinetics via the analysis of fluorescence time traces is often confounded by measurement noise and photophysics. Although photoblinking can be mitigated by using labels less likely...
2.
Panconi L, Euchner J, Tashev S, Makarova M, Herten D, Owen D, et al.
Nat Commun
. 2024 Nov;
15(1):9641.
PMID: 39511199
The mammalian plasma membrane is known to contain domains with varying lipid composition and biophysical properties. However, studying these membrane lipid domains presents challenges due to their predicted morphological similarity...
3.
Tashev S, Euchner J, Yserentant K, Hanselmann S, Hild F, Chmielewicz W, et al.
Nat Methods
. 2024 Aug;
21(9):1708-1715.
PMID: 39117875
Determining the label to target ratio, also known as the degree of labeling (DOL), is crucial for quantitative fluorescence microscopy and a high DOL with minimal unspecific labeling is beneficial...
4.
Clark J, Martin E, Moran L, Di Y, Wang X, Zuidscherwoude M, et al.
Commun Biol
. 2023 Apr;
6(1):376.
PMID: 37029319
CLEC-2 is a target for a new class of antiplatelet agent. Clustering of CLEC-2 leads to phosphorylation of a cytosolic YxxL and binding of the tandem SH2 domains in Syk,...
5.
Hild F, Werther P, Yserentant K, Wombacher R, Herten D
Biophys Rep (N Y)
. 2022 Dec;
2(4):100084.
PMID: 36570717
Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, -cyclooctene (TCO) and bicyclonyne have been found to be the...
6.
Muzzopappa F, Hummert J, Anfossi M, Tashev S, Herten D, Erdel F
Nat Commun
. 2022 Dec;
13(1):7787.
PMID: 36526633
Cells contain numerous substructures that have been proposed to form via liquid-liquid phase separation (LLPS). It is currently debated how to reliably distinguish LLPS from other mechanisms. Here, we benchmark...
7.
Ziegler M, Yserentant K, Dunsing V, Middel V, Gralak A, Pakari K, et al.
Nat Chem Biol
. 2021 Dec;
18(1):64-69.
PMID: 34934192
Direct control of protein interactions by chemically induced protein proximity holds great potential for both cell and synthetic biology as well as therapeutic applications. Low toxicity, orthogonality and excellent cell...
8.
Hummert J, Yserentant K, Fink T, Euchner J, Ho Y, Tashev S, et al.
Mol Biol Cell
. 2021 Sep;
32(21):ar35.
PMID: 34586828
The counting of discrete photobleaching steps in fluorescence microscopy is ideally suited to study protein complex stoichiometry in situ. The counting range of photobleaching step analysis has been significantly improved...
9.
Werther P, Yserentant K, Braun F, Grussmayer K, Navikas V, Yu M, et al.
ACS Cent Sci
. 2021 Sep;
7(9):1561-1571.
PMID: 34584958
Small-molecule fluorophores enable the observation of biomolecules in their native context with fluorescence microscopy. Specific labeling via bio-orthogonal tetrazine chemistry combines minimal label size with rapid labeling kinetics. At the...
10.
Navikas V, Leitao S, Grussmayer K, Descloux A, Drake B, Yserentant K, et al.
Nat Commun
. 2021 Jul;
12(1):4565.
PMID: 34315910
High-resolution live-cell imaging is necessary to study complex biological phenomena. Modern fluorescence microscopy methods are increasingly combined with complementary, label-free techniques to put the fluorescence information into the cellular context....