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Dingchang Lin

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Articles 41
Citations 1811
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Recent Articles
1.
Torkzaban B, Zhu Y, Lopez C, Alexander J, Ma J, Sun Y, et al.
Mol Ther Nucleic Acids . 2025 Feb; 36(1):102453. PMID: 39967850
Polyadenosine (poly(A)) tails are nearly ubiquitous in human messenger RNA (mRNA) governing mRNA stability and translation. Crucially, the poly(A) tail regulates cytoplasmic gene expression by undergoing controlled removal upon exposure...
2.
Ni Q, Ge Z, Li Y, Shatkin G, Fu J, Sen A, et al.
Cell Rep . 2024 Nov; 43(12):114992. PMID: 39579355
Mammalian cells rapidly respond to environmental changes by altering transmembrane water and ion fluxes, changing cell volume. Contractile forces generated by actomyosin have been proposed to mechanically regulate cell volume....
3.
Lee J, Pyo Y, Kim Y, Hong J, Jo Y, Choi W, et al.
Nat Commun . 2023 Nov; 14(1):7088. PMID: 37925553
Electrophysiological recording technologies can provide valuable insights into the functioning of the central and peripheral nervous systems. Surface electrode arrays made of soft materials or implantable multi-electrode arrays with high...
4.
Lin D, Lee J, Wang C, Park H, Lieber C
Nano Lett . 2023 Jun; 23(13):6184-6192. PMID: 37338198
Spinal cord neuromodulation can restore partial to complete loss of motor functions associated with neuromotor disease and trauma. Current technologies have made substantial progress but have limitations as dorsal epidural...
5.
Lee J, Lin D, Pyo Y, Kim H, Park H, Lieber C
Adv Sci (Weinh) . 2023 May; 10(16):e2300220. PMID: 37127888
Understanding complex neuronal networks requires monitoring long-term neuronal activity in various regions of the brain. Significant progress has been made in multisite implantations of well-designed probes, such as multisite implantation...
6.
Lin D, Li X, Moult E, Park P, Tang B, Shen H, et al.
Nat Biotechnol . 2023 Jan; 41(5):631-639. PMID: 36593408
Recording transcriptional histories of a cell would enable deeper understanding of cellular developmental trajectories and responses to external perturbations. Here we describe an engineered protein fiber that incorporates diverse fluorescent...
7.
Lee J, Lin D, Hong G, Kim K, Park H, Lieber C
Nano Lett . 2022 May; 22(11):4552-4559. PMID: 35583378
Electrophysiological recording technologies can provide critical insight into the function of the nervous system and other biological tissues. Standard silicon-based probes have limitations, including single-sided recording sites and intrinsic instabilities...
8.
Lee J, Lin D, Kim H, Pyo Y, Hong G, Lieber C, et al.
Nano Lett . 2021 Mar; 21(7):3184-3190. PMID: 33734716
The development of a multifunctional device that achieves optogenetic neuromodulation and extracellular neural mapping is crucial for understanding neural circuits and treating brain disorders. Although various devices have been explored...
9.
Tran N, Shekhar K, Whitney I, Jacobi A, Benhar I, Hong G, et al.
Neuron . 2019 Dec; 104(6):1039-1055.e12. PMID: 31784286
Neuronal types in the central nervous system differ dramatically in their resilience to injury or other insults. Here we studied the selective resilience of mouse retinal ganglion cells (RGCs) following...
10.
Lee J, Hong G, Lin D, Schuhmann Jr T, Sullivan A, Viveros R, et al.
Nano Lett . 2019 Jul; 19(8):5818-5826. PMID: 31361503
Polymer-based electronics with low bending stiffnesses and high flexibility, including recently reported macroporous syringe-injectable mesh electronics, have shown substantial promise for chronic studies of neural circuitry in the brains of...