Dina A Faddah
Overview
Explore the profile of Dina A Faddah including associated specialties, affiliations and a list of published articles.
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15
Citations
1919
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0
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Recent Articles
1.
Lasry R, Maoz N, Cheng A, Yom Tov N, Kulenkampff E, Azagury M, et al.
Stem Cell Reports
. 2023 Oct;
18(11):2174-2189.
PMID: 37832543
A complete knockout of a single key pluripotency gene may drastically affect embryonic stem cell function and epigenetic reprogramming. In contrast, elimination of only one allele of a single pluripotency...
2.
Wang A, Chiou J, Poirion O, Buchanan J, Valdez M, Verheyden J, et al.
Elife
. 2020 Nov;
9.
PMID: 33164753
Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we present single-nucleus accessible chromatin profiles of 90,980 nuclei and matched single-nucleus transcriptomes of 46,500 nuclei in non-diseased...
3.
Theunissen T, Powell B, Wang H, Mitalipova M, Faddah D, Reddy J, et al.
Cell Stem Cell
. 2017 Sep;
15(4):524-526.
PMID: 28903030
No abstract available.
4.
Theunissen T, Powell B, Wang H, Mitalipova M, Faddah D, Reddy J, et al.
Cell Stem Cell
. 2017 Sep;
15(4):523.
PMID: 28903029
No abstract available.
5.
Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, et al.
Cell Stem Cell
. 2014 Sep;
15(3):295-309.
PMID: 25192464
Induced pluripotent stem cells (iPSCs) are commonly generated by transduction of Oct4, Sox2, Klf4, and Myc (OSKM) into cells. Although iPSCs are pluripotent, they frequently exhibit high variation in terms...
6.
Theunissen T, Powell B, Wang H, Mitalipova M, Faddah D, Reddy J, et al.
Cell Stem Cell
. 2014 Aug;
15(4):471-487.
PMID: 25090446
Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological characteristics, raising the question of whether an earlier, "naive" state of pluripotency may exist in humans. Here...
7.
Klemm S, Semrau S, Wiebrands K, Mooijman D, Faddah D, Jaenisch R, et al.
Nat Methods
. 2014 Apr;
11(5):549-551.
PMID: 24681693
We have developed a quantitative technique for sorting cells on the basis of endogenous RNA abundance, with a molecular resolution of 10-20 transcripts. We demonstrate efficient and unbiased RNA extraction...
8.
Faddah D, Wang H, Cheng A, Katz Y, Buganim Y, Jaenisch R
Cell Stem Cell
. 2013 Jul;
13(1):23-9.
PMID: 23827708
The homeodomain transcription factor Nanog is a central part of the core pluripotency transcriptional network and plays a critical role in embryonic stem cell (ESC) self-renewal. Several reports have suggested...
9.
Buganim Y, Faddah D, Jaenisch R
Nat Rev Genet
. 2013 May;
14(6):427-39.
PMID: 23681063
Conversion of somatic cells to pluripotency by defined factors is a long and complex process that yields embryonic-stem-cell-like cells that vary in their developmental potential. To improve the quality of...
10.
Buganim Y, Faddah D, Cheng A, Itskovich E, Markoulaki S, Ganz K, et al.
Cell
. 2012 Sep;
150(6):1209-22.
PMID: 22980981
During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell...