Dimitris K Grammatopoulos
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Explore the profile of Dimitris K Grammatopoulos including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Mytilinaiou M, Kyrou I, Khan M, Grammatopoulos D, Randeva H
Front Pharmacol
. 2018 Jul;
9:707.
PMID: 30050433
Familial hypercholesterolemia (FH) is a common genetic cause of premature cardiovascular disease (CVD). The reported prevalence rates for both heterozygous FH (HeFH) and homozygous FH (HoFH) vary significantly, and this...
12.
Dimitriadis G, Randeva H, Aftab S, Ali A, Hattersley J, Pandey S, et al.
Endocrine
. 2018 Feb;
60(1):175-184.
PMID: 29396841
Aim: To explore the metabolic phenotype of obesity-related secondary hypogonadism (SH) in men pre-replacement and post-replacement therapy with long-acting intramuscular (IM) testosterone undecanoate (TU). Methods: A prospective observational pilot study...
13.
Xue M, Shafie A, Qaiser T, Rajpoot N, Kaltsas G, James S, et al.
Oncotarget
. 2017 Nov;
8(44):76961-76973.
PMID: 29100361
Background: The glyoxalase-1 gene (GLO1) is a hotspot for copy-number variation (CNV) in human genomes. Increased GLO1 copy-number is associated with multidrug resistance in tumour chemotherapy, but prevalence of GLO1...
14.
Alcantara-Alonso V, Panetta P, de Gortari P, Grammatopoulos D
Front Endocrinol (Lausanne)
. 2017 Jul;
8:161.
PMID: 28744256
A balanced interaction between the homeostatic mechanisms of mother and the developing organism during pregnancy and in early neonatal life is essential in order to ensure optimal fetal development, ability...
15.
Hasdemir B, Mahajan S, Oses-Prieto J, Chand S, Woolley M, Burlingame A, et al.
Mol Biol Cell
. 2017 Jul;
28(18):2386-2399.
PMID: 28701349
Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein-coupled receptors, are...
16.
Hanyaloglu A, Grammatopoulos D
Mol Cell Endocrinol
. 2017 May;
449:1-2.
PMID: 28528660
No abstract available.
17.
Grammatopoulos D
Mol Cell Endocrinol
. 2017 Feb;
449:82-89.
PMID: 28229904
G-protein coupled receptors (GPCRs) have long been at the center of investigations of the neurobiology of depression and mood disorders. Different facets of GPCR signalling pathways, including those controlling monoaminergic...
18.
Dimitriadis G, Kaltsas G, Ghobara T, Sinha B, Drakou E, Gopalakrishnan K, et al.
Am J Med
. 2017 Feb;
130(6):e261-e263.
PMID: 28161346
No abstract available.
19.
Grammatopoulos D, Ourailidou S
Curr Mol Pharmacol
. 2017 Jan;
10(4):296-310.
PMID: 28103786
To maintain homeostatic equilibrium, living organisms have evolved complex adaptation systems that control an array of behavioural, autonomic, neuroendocrine and immune responses. One of the important switches of this system...
20.
Reiman A, Pandey S, Lloyd K, Dyer N, Khan M, Crockard M, et al.
Ann Clin Biochem
. 2016 Jan;
53(6):654-662.
PMID: 26748104
Background Detection of disease-associated mutations in patients with familial hypercholesterolaemia is crucial for early interventions to reduce risk of cardiovascular disease. Screening for these mutations represents a methodological challenge since...