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Dimitrios Tsiantoulas

Explore the profile of Dimitrios Tsiantoulas including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1325
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Recent Articles
1.
Juhasz V, Charlier F, Zhao T, Tsiantoulas D
Atherosclerosis . 2024 Nov; 399:118616. PMID: 39546915
Atherosclerotic disease is a cholesterol-rich lipoprotein particle-driven disease resulting in the formation of atherosclerotic plaques in large and medium size arteries. Rupture or erosion of atherosclerotic plaques can trigger the...
2.
Takaoka M, Zhao X, Lim H, Magnussen C, Ang O, Suffee N, et al.
Nature . 2024 Sep; 634(8033):457-465. PMID: 39231480
Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD). Risk of cardiovascular events depends on cumulative lifetime exposure to low-density lipoprotein cholesterol (LDL-C) and, independently, on the time...
3.
Tsiantoulas D, Binder C
Nat Cardiovasc Res . 2024 Aug; 3(2):243. PMID: 39196203
No abstract available.
4.
Tsiantoulas D, Binder C
Nat Cardiovasc Res . 2024 Aug; 3(2):106-107. PMID: 39196191
No abstract available.
5.
Kiss M, Papac-Milicevic N, Porsch F, Tsiantoulas D, Hendrikx T, Takaoka M, et al.
Immunity . 2023 Jul; 56(8):1809-1824.e10. PMID: 37499656
Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby restricting complement activation. Genetic variants in CFH predispose to chronic inflammatory disease. Here, we examined the impact...
6.
Smit V, de Mol J, Schaftenaar F, Depuydt M, Postel R, Smeets D, et al.
Cardiovasc Res . 2023 Jun; 119(15):2508-2521. PMID: 37390467
Aims: Aging is a dominant driver of atherosclerosis and induces a series of immunological alterations, called immunosenescence. Given the demographic shift towards elderly, elucidating the unknown impact of aging on...
7.
Bonacina F, Di Costanzo A, Genkel V, Kong X, Kroon J, Stimjanin E, et al.
Atherosclerosis . 2023 Apr; 372:48-56. PMID: 37030081
Single cell technologies, lineage tracing mouse models and advanced imaging techniques unequivocally improved the resolution of the cellular landscape of atherosclerosis. Although the discovery of the heterogeneous nature of the...
8.
Smeets D, Gistera A, Malin S, Tsiantoulas D
Front Cardiovasc Med . 2022 May; 9:864602. PMID: 35497984
B cells are a core element of the pathophysiology of atherosclerotic cardiovascular disease (ASCVD). Multiple experimental and epidemiological studies have revealed both protective and deleterious functions of B cells in...
9.
de Mol J, Kuiper J, Tsiantoulas D, Foks A
Front Immunol . 2021 Oct; 12:733566. PMID: 34675924
Aging is considered to be an important risk factor for several inflammatory diseases. B cells play a major role in chronic inflammatory diseases by antibody secretion, antigen presentation and T...
10.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer F, et al.
Nature . 2021 Aug; 597(7874):92-96. PMID: 34433968
Atherosclerotic cardiovascular disease causes heart attacks and strokes, which are the leading causes of mortality worldwide. The formation of atherosclerotic plaques is initiated when low-density lipoproteins bind to heparan-sulfate proteoglycans...