Dimitrios Kleidonas
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Explore the profile of Dimitrios Kleidonas including associated specialties, affiliations and a list of published articles.
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8
Citations
42
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Recent Articles
1.
Zhao S, Wang L, Kleidonas D, Qi F, Liang Y, Zheng J, et al.
Sci Adv
. 2025 Feb;
11(9):eado7829.
PMID: 40020068
Microglia actively survey the brain and dynamically interact with neurons to maintain brain homeostasis. Microglial Gi protein-coupled receptors (Gi-GPCRs) play a critical role in microglia-neuron communications. However, the impact of...
2.
Kleidonas D, Hilfiger L, Lenz M, Haussinger D, Vlachos A
Front Cell Neurosci
. 2024 Oct;
18:1410275.
PMID: 39411004
Acute liver dysfunction commonly leads to rapid increases in ammonia concentrations in both the serum and the cerebrospinal fluid. These elevations primarily affect brain astrocytes, causing modifications in their structure...
3.
Lenz M, Eichler A, Kruse P, Galanis C, Kleidonas D, Andrieux G, et al.
J Neurosci
. 2023 Jun;
43(29):5290-5304.
PMID: 37369586
The perforant path provides the primary cortical excitatory input to the hippocampus. Because of its important role in information processing and coding, entorhinal projections to the dentate gyrus have been...
4.
Kleidonas D, Kirsch M, Andrieux G, Pfeifer D, Boerries M, Vlachos A
Glia
. 2023 May;
71(9):2117-2136.
PMID: 37208965
The pro-inflammatory cytokine tumor necrosis factor α (TNFα) tunes the capacity of neurons to express synaptic plasticity. It remains, however, unclear how TNFα mediates synaptic positive (=change) and negative (=stability)...
5.
Lenz M, Eichler A, Kruse P, Stohr P, Kleidonas D, Galanis C, et al.
Front Mol Neurosci
. 2023 May;
16:1148219.
PMID: 37122623
Structural, functional, and molecular reorganization of denervated neural networks is often observed in neurological conditions. The loss of input is accompanied by homeostatic synaptic adaptations, which can affect the reorganization...
6.
Eichler A, Kleidonas D, Turi Z, Fliegauf M, Kirsch M, Pfeifer D, et al.
J Neurosci
. 2023 Mar;
43(17):3042-3060.
PMID: 36977586
Microglia, the resident immune cells of the CNS, sense the activity of neurons and regulate physiological brain functions. They have been implicated in the pathology of brain diseases associated with...
7.
Kalogeropoulos K, Kleidonas D, Psarropoulou C
Epilepsia Open
. 2022 Jul;
7(4):608-615.
PMID: 35908206
Objective: To investigate the effect of generating mechanism on the relationship between interictal-like epileptiform discharges (IEDs) and the underlying High Frequency Oscillations (HFOs; Ripples, R, and Fast Ripples, FR). Methods:...
8.
Kleidonas D, Vlachos A
Cells
. 2021 Nov;
10(11).
PMID: 34831454
Neurons that lose part of their afferent input remodel their synaptic connections. While cellular and molecular mechanisms of denervation-induced changes in excitatory neurotransmission have been identified, little is known about...
9.
Lenz M, Galanis C, Kleidonas D, Fellenz M, Deller T, Vlachos A
Exp Neurol
. 2018 Nov;
312:1-9.
PMID: 30401642
Neurons adjust their synaptic strength in a homeostatic manner following changes in network activity and connectivity. While this form of plasticity has been studied in detail for excitatory synapses, homeostatic...