Dimitrios A Garyfallos
Overview
Explore the profile of Dimitrios A Garyfallos including associated specialties, affiliations and a list of published articles.
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7
Citations
312
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Recent Articles
1.
Triller G, Garyfallos D, Papavasiliou F, Sklaviadis T, Stavropoulos P, Xanthopoulos K
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142526
Transmissible spongiform encephalopathies are incurable neurodegenerative diseases, associated with the conversion of the physiological prion protein to its disease-associated counterpart. Even though immunization against transmissible spongiform encephalopathies has shown great...
2.
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al.
Nat Genet
. 2022 Jun;
54(7):1062.
PMID: 35701672
No abstract available.
3.
Orellana E, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, et al.
Mol Cell
. 2021 Aug;
81(16):3323-3338.e14.
PMID: 34352207
The emerging "epitranscriptomics" field is providing insights into the biological and pathological roles of different RNA modifications. The RNA methyltransferase METTL1 catalyzes N7-methylguanosine (mG) modification of tRNAs. Here we find...
4.
Kotsaris G, Kerselidou D, Koutsoubaris D, Constantinou E, Malamas G, Garyfallos D, et al.
J Biol Res (Thessalon)
. 2020 Jun;
27:7.
PMID: 32514408
Background: Members of Tumor Necrosis Factor (TNF) Receptor-Associated Factors (TRAFs) family interact with the cytoplasmic tails of TNF receptor family members to mediate signal transduction processes. TRAF3 has a major...
5.
Yang J, Rajan S, Friedrich M, Lan G, Zou X, Ponstingl H, et al.
Stem Cell Reports
. 2019 Mar;
12(4):757-771.
PMID: 30905739
Primed epiblast stem cells (EpiSCs) can be reverted to a pluripotent embryonic stem cell (ESC)-like state by expression of single reprogramming factor. We used CRISPR activation to perform a genome-scale,...
6.
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar M, Liu W, et al.
Nat Commun
. 2018 Dec;
9(1):5378.
PMID: 30568163
We recently identified the splicing kinase gene SRPK1 as a genetic vulnerability of acute myeloid leukemia (AML). Here, we show that genetic or pharmacological inhibition of SRPK1 leads to cell...
7.
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al.
Nat Genet
. 2018 May;
50(6):883-894.
PMID: 29736013
The histone H3 Lys27-specific demethylase UTX (or KDM6A) is targeted by loss-of-function mutations in multiple cancers. Here, we demonstrate that UTX suppresses myeloid leukemogenesis through noncatalytic functions, a property shared...