Dilansu Guneykaya
Overview
Explore the profile of Dilansu Guneykaya including associated specialties, affiliations and a list of published articles.
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7
Citations
356
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Recent Articles
1.
Brandao W, Jain N, Yin Z, Kleemann K, Carpenter M, Bao X, et al.
Sci Transl Med
. 2025 Jan;
17(781):eadk3690.
PMID: 39813317
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Antiamyloid antibody treatments modestly slow disease progression in mild dementia due to AD. Emerging evidence shows that homeostatic dysregulation of the...
2.
Guneykaya D, Ugursu B, Logiacco F, Popp O, Feiks M, Meyer N, et al.
Brain Behav Immun
. 2023 Mar;
111:61-75.
PMID: 37001827
Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and behavioral phenotypes. Microglia, the resident CNS macrophages, are implicated in...
3.
Fiore N, Yin Z, Guneykaya D, Gauthier C, Hayes J, DHary A, et al.
Glia
. 2022 Jan;
70(4):675-696.
PMID: 35050555
Neuropathic pain is a prevalent and debilitating chronic disease that is characterized by activation in glial cells in various pain-related regions within the central nervous system. Recent studies have suggested...
4.
let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
Buonfiglioli A, Efe I, Guneykaya D, Ivanov A, Huang Y, Orlowski E, et al.
Cell Rep
. 2019 Dec;
29(11):3460-3471.e7.
PMID: 31825829
Microglia express Toll-like receptors (TLRs) that sense pathogen- and host-derived factors, including single-stranded RNA. In the brain, let-7 microRNA (miRNA) family members are abundantly expressed, and some have recently been...
5.
Guneykaya D, Ivanov A, Perez Hernandez D, Haage V, Wojtas B, Meyer N, et al.
Cell Rep
. 2018 Sep;
24(10):2773-2783.e6.
PMID: 30184509
Sex differences in brain structure and function are of substantial scientific interest because of sex-related susceptibility to psychiatric and neurological disorders. Neuroinflammation is a common denominator of many of these...
6.
Szulzewsky F, Schwendinger N, Guneykaya D, Cimino P, Hambardzumyan D, Synowitz M, et al.
Neuro Oncol
. 2017 Oct;
20(3):355-366.
PMID: 29016864
Background: Microglia and periphery-derived monocytes infiltrate human and mouse glioblastoma and their density is positively correlated with malignancy. Using microarray and RNA sequencing, we have previously shown that glioblastoma-associated microglia/monocytes...
7.
Wendt S, Maricos M, Vana N, Meyer N, Guneykaya D, Semtner M, et al.
Neurobiol Aging
. 2017 Jul;
58:41-53.
PMID: 28697378
As the immunocompetent cells of the central nervous system, microglia accumulate at amyloid beta plaques in Alzheimer's disease (AD) and acquire a morphological phenotype of activated microglia. Recent functional studies,...
8.
Hadar R, Dong L, Del-Valle-Anton L, Guneykaya D, Voget M, Edemann-Callesen H, et al.
Brain Behav Immun
. 2016 Dec;
63:71-80.
PMID: 27939248
In recent years schizophrenia has been recognized as a neurodevelopmental disorder likely involving a perinatal insult progressively affecting brain development. The poly I:C maternal immune activation (MIA) rodent model is...