Didier Keh
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Explore the profile of Didier Keh including associated specialties, affiliations and a list of published articles.
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41
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3291
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Recent Articles
1.
Pirracchio R, Annane D, Waschka A, Lamontagne F, Arabi Y, Bollaert P, et al.
NEJM Evid
. 2024 Feb;
2(6):EVIDoa2300034.
PMID: 38320130
BACKGROUND: Trials and study-level meta-analyses have failed to resolve the role of corticosteroids in the management of patients with septic shock. Patient-level meta-analyses may provide more precise estimates of treatment...
2.
Schmoch T, Mohnle P, Weigand M, Briegel J, Bauer M, Bloos F, et al.
Ann Intensive Care
. 2023 Jan;
13(1):3.
PMID: 36635426
Background: Sepsis and septic shock are frequently accompanied by coagulopathy. Since the sepsis-induced coagulopathy (SIC) score was first described, subsequent studies from Asia revealed a SIC prevalence of 40-60%. In...
3.
Briegel J, Mohnle P, Keh D, Lindner J, Vetter A, Bogatsch H, et al.
Crit Care
. 2022 Nov;
26(1):343.
PMID: 36345013
Rationale: Steroid profiles in combination with a corticotropin stimulation test provide information about steroidogenesis and its functional reserves in critically ill patients. Objectives: We investigated whether steroid profiles before and...
4.
Konig R, Kolte A, Ahlers O, Oswald M, Krauss V, Roell D, et al.
Front Immunol
. 2021 Mar;
12:607217.
PMID: 33767693
Large clinical trials testing hydrocortisone therapy in septic shock have produced conflicting results. Subgroups may benefit of hydrocortisone treatment depending on their individual immune response. We performed an exploratory analysis...
5.
Annane D, Bellissant E, Bollaert P, Briegel J, Keh D, Kupfer Y, et al.
Emergencias
. 2021 Mar;
33(2):137-138.
PMID: 33750056
No abstract available.
6.
Knaak C, Schuster F, Nyvlt P, Spies C, Feinkohl I, Beutel G, et al.
Crit Care Med
. 2020 Sep;
48(11):e1137-e1146.
PMID: 32947471
Objectives: Hemophagocytic lymphohistiocytosis is a cytokine release syndrome caused by uncontrolled immune activation resulting in multiple organ failure and death. In this systematic review, we aimed to analyze triggers, various...
7.
Knaak C, Nyvlt P, Schuster F, Spies C, Heeren P, Schenk T, et al.
Crit Care
. 2020 May;
24(1):244.
PMID: 32448380
Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have...
8.
Lachmann G, Knaak C, Vorderwulbecke G, La Rosee P, Balzer F, Schenk T, et al.
Crit Care Med
. 2020 Mar;
48(4):459-465.
PMID: 32205591
Objective: Hyperferritinemia is frequently seen in critically ill patients. A rather rare though life-threatening condition related to severely elevated ferritin is hemophagocytic lymphohistiocytosis. We analyze ferritin levels to differentiate hemophagocytic...
9.
Annane D, Bellissant E, Bollaert P, Briegel J, Keh D, Kupfer Y, et al.
Cochrane Database Syst Rev
. 2019 Dec;
12:CD002243.
PMID: 31808551
Background: Sepsis occurs when an infection is complicated by organ failure. Sepsis may be complicated by impaired corticosteroid metabolism. Thus, providing corticosteroids may benefit patients. The original review was published...
10.
Lachmann G, Knaak C, Von Haefen C, Paeschke N, Meisel C, Nyvlt P, et al.
BMJ Open
. 2019 Nov;
9(10):e032695.
PMID: 31666276
Introduction: Haemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%....