Didier Flament
Overview
Explore the profile of Didier Flament including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
533
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0
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Recent Articles
1.
Batista M, Langendijk-Genevaux P, Kwapisz M, Canal I, Phung D, Plassart L, et al.
NAR Genom Bioinform
. 2024 Mar;
6(1):lqae026.
PMID: 38500564
RNA helicases perform essential housekeeping and regulatory functions in all domains of life by binding and unwinding RNA molecules. The Ski2-like proteins are primordial helicases that play an active role...
2.
Mc Teer L, Moalic Y, Cueff-Gauchard V, Catchpole R, Hogrel G, Lu Y, et al.
mBio
. 2024 Feb;
15(4):e0320023.
PMID: 38421162
Importance: Replication of DNA is highly important in all organisms. It initiates at a specific locus called , which serves as the binding site for scaffold proteins-either Cdc6 or DnaA-depending...
3.
Madru C, Martinez-Carranza M, Laurent S, Alberti A, Chevreuil M, Raynal B, et al.
Nat Commun
. 2023 Apr;
14(1):2326.
PMID: 37087464
Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, recombination and repair. Little is known about the structure of RPA in Archaea,...
4.
Carre L, Henneke G, Henry E, Flament D, Girard E, Franzetti B
Astrobiology
. 2023 Jan;
24(2):151-162.
PMID: 36622808
Evidence of stable liquid water oceans beneath the ice crust of moons within the Solar System is of great interest for astrobiology. In particular, subglacial oceans may present hydrothermal processes...
5.
Characterization of a small tRNA-binding protein that interacts with the archaeal proteasome complex
Hogrel G, Marino-Puertas L, Laurent S, Ibrahim Z, Coves J, Girard E, et al.
Mol Microbiol
. 2022 May;
118(1-2):16-29.
PMID: 35615908
The proteasome system allows the elimination of functional or structurally impaired proteins. This includes the degradation of nascent peptides. In Archaea, how the proteasome complex interacts with the translational machinery...
6.
Hajj M, Langendijk-Genevaux P, Batista M, Quentin Y, Laurent S, Capeyrou R, et al.
Biomolecules
. 2021 Jul;
11(7).
PMID: 34206878
Helicase proteins are known to use the energy of ATP to unwind nucleic acids and to remodel protein-nucleic acid complexes. They are involved in almost every aspect of DNA and...
7.
Hogrel G, Lu Y, Alexandre N, Bosse A, Dulermo R, Ishino S, et al.
Biomolecules
. 2020 Jul;
10(7).
PMID: 32674430
Among the three domains of life, the process of homologous recombination (HR) plays a central role in the repair of double-strand DNA breaks and the restart of stalled replication forks....
8.
Phung D, Etienne C, Batista M, Langendijk-Genevaux P, Moalic Y, Laurent S, et al.
Nucleic Acids Res
. 2020 Feb;
48(7):3832-3847.
PMID: 32030412
A network of RNA helicases, endoribonucleases and exoribonucleases regulates the quantity and quality of cellular RNAs. To date, mechanistic studies focussed on bacterial and eukaryal systems due to the challenge...
9.
Hogrel G, Lu Y, Laurent S, Henry E, Etienne C, Phung D, et al.
Nucleic Acids Res
. 2018 May;
46(11):5651-5663.
PMID: 29741662
Several archaeal species prevalent in extreme environments are particularly exposed to factors likely to cause DNA damages. These include hyperthermophilic archaea (HA), living at temperatures >70°C, which arguably have efficient...
10.
Birien T, Thiel A, Henneke G, Flament D, Moalic Y, Jebbar M
Genes (Basel)
. 2018 Feb;
9(2).
PMID: 29414865
A gene disruption system for was developed using simvastatin (HMG-CoA reductase encoding gene) for positive selection and 5-Fluoroorotic acid (5-FOA), a gene for negative selection. Multiple gene mutants were constructed...