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Dianna L Shipley

Explore the profile of Dianna L Shipley including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 307
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Recent Articles
1.
Spigel D, Shipley D, Waterhouse D, Jones S, Ward P, Shih K, et al.
Oncologist . 2019 Aug; 24(12):e1409-e1416. PMID: 31420467
Background: This randomized, double-blinded, phase II trial evaluated the efficacy of carboplatin and pemetrexed plus either apatorsen, an antisense oligonucleotide targeting heat shock protein (Hsp) 27 mRNA, or placebo in...
2.
Spigel D, Hainsworth J, Shipley D, Mekhail T, Zubkus J, Waterhouse D, et al.
Lung Cancer . 2018 Mar; 117:38-43. PMID: 29496254
Purpose: First-line treatment for patients with extensive-stage small cell lung cancer (SCLC) includes treatment with platinum-based combination chemotherapy. Amrubicin is a synthetic anthracycline with single-agent activity in relapsed/refractory SCLC. In...
3.
Spigel D, Hainsworth J, Joseph M, Shipley D, Hagan M, Thompson D, et al.
Cancer . 2018 Feb; 124(9):1982-1991. PMID: 29451696
Background: The best treatment for patients with advanced non-small cell lung cancer (NSCLC) and a poor performance status is not well defined. In this phase 2 trial, patients were randomized...
4.
Spigel D, Rubin M, Gian V, Shipley D, Burris 3rd H, Kosloff R, et al.
Lung Cancer . 2017 Nov; 113:79-84. PMID: 29110854
Purpose: To evaluate the efficacy of erlotinib, continued after tumor progression, plus sorafenib versus sorafenib alone in patients with refractory metastatic non-small cell lung cancer (NSCLC) who previously benefitted from...
5.
Ko A, Murphy P, Peyton J, Shipley D, Al-Hazzouri A, Rodriguez F, et al.
Oncologist . 2017 Sep; 22(12):1427-e129. PMID: 28935773
Lessons Learned: The addition of the heat shock protein 27 (Hsp27)-targeting antisense oligonucleotide, apatorsen, to a standard first-line chemotherapy regimen did not result in improved survival in unselected patients with...
6.
Yardley D, Shipley D, Peacock N, Shastry M, Midha R, Priego V, et al.
Breast Cancer Res Treat . 2015 Jul; 152(3):557-67. PMID: 26155975
The purpose of the study is to evaluate the feasibility and efficacy of adding sunitinib to paclitaxel/carboplatin in the neoadjuvant therapy of patients with triple-negative breast cancer (TNBC). Patients had...
7.
Hainsworth J, Shipley D, Reeves Jr J, Arrowsmith E, Barnes E, Waterhouse D
Clin Genitourin Cancer . 2013 May; 11(3):283-289.e1. PMID: 23684421
Background: The dose of bevacizumab necessary to optimally inhibit tumor angiogenesis in advanced renal cell carcinoma is unknown. In this phase II trial, we evaluated the efficacy and safety of...
8.
Hainsworth J, Waterhouse D, Penley W, Shipley D, Thompson D, Webb C, et al.
Cancer Invest . 2013 Apr; 31(5):323-9. PMID: 23614653
Purpose: To evaluate the feasibility and efficacy of sorafenib and everolimus in renal cell carcinoma (RCC). Methods: Patients with advanced RCC and ≤ 1 previous targeted therapy were treated. Results:...
9.
Spigel D, Greco F, Waterhouse D, Shipley D, Zubkus J, Bury M, et al.
Lung Cancer . 2012 Sep; 78(1):70-5. PMID: 22947511
Background: Epothilones, a new class of cytotoxic agents, have demonstrated activity in non-small-cell lung cancer (NSCLC). This phase II study examined ixabepilone/carboplatin (cohort A) and ixabepilone/carboplatin/bevacizumab (cohort B) as first-line...
10.
Hainsworth J, Spigel D, Greco F, Shipley D, Peyton J, Rubin M, et al.
Cancer J . 2011 Sep; 17(5):267-72. PMID: 21952273
Purpose: : The aim of the study was to evaluate the feasibility and efficacy of adding bevacizumab and erlotinib to concurrent chemoradiation therapy for first-line treatment of patients with locally...