Diane Ouwerkerk
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Explore the profile of Diane Ouwerkerk including associated specialties, affiliations and a list of published articles.
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20
Citations
337
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Recent Articles
1.
Hungerford N, Ouwerkerk D, Gilbert R, Loh Z, Gordon R, Silva L, et al.
J Agric Food Chem
. 2024 Jul;
72(28):15572-15585.
PMID: 38958707
poisoning of cattle causes distinct symptoms and frequently death, attributable to the toxin simplexin. poisoning was induced via addition of ground plant to the daily feed in a three-month trial...
2.
Zhou Y, Roseli R, Hungerford N, Fletcher M, Ouwerkerk D, Gilbert R, et al.
Org Biomol Chem
. 2024 Mar;
22(14):2863-2876.
PMID: 38525790
poisoning of cattle is toxicologically linked to the activation of bovine protein kinase C (PKC) by the plant-derived toxin simplexin. To understand the affinity of PKC for simplexin, we performed...
3.
Gilbert R, Davis C, Gravel J, Ouwerkerk D
Microbiol Resour Announc
. 2024 Mar;
13(4):e0101223.
PMID: 38501784
We report the 2.78-Mb circular genome sequence of sp. strain YE332, isolated from a fermentation of bovine rumen fluid, supplied with leaf material from cv. Cunningham. This genome sequence consists...
4.
Loh Z, Hungerford N, Ouwerkerk D, Klieve A, Fletcher M
Toxins (Basel)
. 2023 Sep;
15(9).
PMID: 37755977
Pimelea poisoning of cattle is a unique Australian toxic condition caused by the daphnane orthoester simplexin present in native Pimelea pasture plants. Rumen microorganisms have been proposed to metabolise simplexin...
5.
Bajagai Y, Yeoh Y, Li X, Zhang D, Dennis P, Ouwerkerk D, et al.
J Appl Microbiol
. 2023 Apr;
134(5).
PMID: 37096395
Aims: Sub-therapeutic use of antibiotics as a growth promoter in animal diets has either been banned or voluntarily withdrawn from use in many countries to help curb the emergence of...
6.
Yuan Y, Hungerford N, Gauthier E, Ouwerkerk D, Yong K, Fletcher M, et al.
Anal Bioanal Chem
. 2021 Jun;
413(20):5121-5133.
PMID: 34184103
In the present paper, we describe how a robust and fundamental methodology was developed for extraction and determination of a principal natural toxin compound, simplexin, from a series of bulk...
7.
Gilbert R, Netzel G, Chandra K, Ouwerkerk D, Fletcher M
Toxins (Basel)
. 2021 Jun;
13(6).
PMID: 34071579
The leguminous plant species, and are distributed throughout the rangeland regions of Australia and the compound indospicine (L-2-amino-6-amidinohexanoic acid) found in these palatable forage plants acts as a hepatotoxin and...
8.
Loh Z, Ouwerkerk D, Klieve A, Hungerford N, Fletcher M
Toxins (Basel)
. 2020 Oct;
12(10).
PMID: 33092236
Animal feeds may contain exogenous compounds that can induce toxicity when ruminants ingest them. These toxins are secondary metabolites originating from various sources including plants, bacteria, algae and fungi. Animal...
9.
Gilbert R, Townsend E, Crew K, Hitch T, Friedersdorff J, Creevey C, et al.
Front Microbiol
. 2020 Apr;
11:450.
PMID: 32273870
The rumen contains a multi-kingdom, commensal microbiome, including protozoa, bacteria, archaea, fungi and viruses, which enables ruminant herbivores to ferment and utilize plant feedstuffs that would be otherwise indigestible. Within...
10.
Grant L, Mikkelsen D, Phan A, Kang S, Ouwerkerk D, Klieve A, et al.
Food Funct
. 2020 Jan;
11(1):834-845.
PMID: 31932826
A substantial fraction of ingested polyphenols accumulate in the large intestine (LI), attached to undigested plant cell walls (PCW) (dietary fibre). Yet, whether these PCW-bound polyphenols alter the structure and...