Diane Brisson
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Explore the profile of Diane Brisson including associated specialties, affiliations and a list of published articles.
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81
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2089
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Recent Articles
1.
Larouche M, Banerjee P, Brisson D, Pordy R, Gaudet D
J Endocr Soc
. 2025 Mar;
9(4):bvaf025.
PMID: 40046103
Background: Persistent chylomicronemia is caused by lipoprotein lipase deficiency (LPLD) or lack of lipoprotein lipase (LPL) bioavailability. This disorder is characterized by plasma triglyceride (TG) levels above 10 mmol/L, increased...
2.
Lauziere A, Brisson D, Tremblay G, Bedard S, Khoury E, Gaudet D
J Clin Med
. 2025 Jan;
14(2.
PMID: 39860310
Over the past decades, new treatments and guidelines have been introduced for the screening and management of familial hypercholesterolemia (FH). However, the impact of these medical and scientific advances on...
3.
Paquette M, Ruel I, Guay S, Al-Baldawi Z, Brisson D, Gaudet D, et al.
J Clin Lipidol
. 2024 Dec;
19(1):105-113.
PMID: 39638644
Background: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disease of low-density lipoprotein cholesterol (LDL-C) metabolism. Despite the devastating effect of this disease on atherosclerotic cardiovascular health, the disease phenotype...
4.
Larouche M, Bluteau O, Carrie A, Lauziere A, Khoury E, Brisson D, et al.
J Clin Med
. 2024 Oct;
13(19).
PMID: 39407785
Studying patients carrying identical-by-descent (IBD) pathogenic gene variants allows us to control for the disease-causing genetic background and to more accurately document the impact of modifiers. Familial hypercholesterolemia (FH) is...
5.
Inhibition of Angiopoietin-Like Protein 3 or 3/8 Complex and ApoC-III in Severe Hypertriglyceridemia
Larouche M, Khoury E, Brisson D, Gaudet D
Curr Atheroscler Rep
. 2023 Dec;
25(12):1101-1111.
PMID: 38095804
Purpose Of Review: The role of the inhibition of ANGPTL3 in severe or refractory hypercholesterolemia is well documented, less in severe hyperTG. This review focuses on the preclinical and clinical...
6.
Lauziere A, Brisson D, Tremblay G, Bedard S, Khoury E, Gaudet D
J Clin Lipidol
. 2023 Nov;
18(1):e90-e96.
PMID: 38030518
Background: Familial hypercholesterolemia (FH) is associated with lifelong elevated plasma concentrations of low-density lipoprotein cholesterol (LDL-C) and high risk of premature coronary heart disease (CHD). Clinical recommendations and treatments have...
7.
Larouche M, Brisson D, Morissette M, Gaudet D
Orphanet J Rare Dis
. 2023 Jun;
18(1):167.
PMID: 37370069
Background: The familial chylomicronemia syndrome (FCS) is an ultra rare disease caused by lipoprotein lipase (LPL) deficiency associated with potentially lethal acute pancreatitis risk. Thrombocytopenia (platelet count < 150,000 × ...
8.
Brisson D, Larouche M, Chebli J, Khoury E, Gaudet D
Clin Biochem
. 2023 Feb;
114:67-72.
PMID: 36780934
Introduction: Sustained chylomicronemia is a defect in post-prandial triglyceride management characterized by severe hypertriglyceridemia (triglyceride > 10 mmol/L) due to functional or genetic defects in lipoprotein lipase (LPL)-mediated triglyceride-rich lipoprotein...
9.
Sun C, McCudden C, Brisson D, Shaw J, Gaudet D, Ooi T
Can J Cardiol
. 2022 Dec;
39(5):668-677.
PMID: 36586484
Background: Limitations of the Friedewald equation for low-density-lipoprotein cholesterol (F-LDLC) calculation led to the Martin-Hopkins (M-LDLC) and Sampson-National Institutes of Health (S-LDLC) equations. We studied these newer calculations of LDLC...
10.
Roy N, Gaudet D, Brisson D
J Endocr Soc
. 2022 Jul;
6(8):bvac103.
PMID: 35860753
Context: Palmar striated xanthomas (PSX) are macular subcutaneous lesions conferring a yellow-to-orange coloration of palmar and finger creases that characterize dysbetalipoproteinemia, a disease associated with sustained plasma accumulation of triglyceride-rich...