Diana C Spierings
Overview
Explore the profile of Diana C Spierings including associated specialties, affiliations and a list of published articles.
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4
Citations
323
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Recent Articles
1.
Foijer F, Albacker L, Bakker B, Spierings D, Yue Y, Xie S, et al.
Elife
. 2017 Mar;
6.
PMID: 28318489
Chromosome instability (CIN) is deleterious to normal cells because of the burden of aneuploidy. However, most human solid tumors have an abnormal karyotype implying that gain and loss of chromosomes...
2.
Levine M, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, et al.
Dev Cell
. 2017 Jan;
40(3):313-322.e5.
PMID: 28132847
Centrosome amplification is a common feature of human tumors, but whether this is a cause or a consequence of cancer remains unclear. Here, we test the consequence of centrosome amplification...
3.
Spierings D, McGoldrick D, Hamilton-Easton A, Neale G, Murchison E, Hannon G, et al.
Blood
. 2011 Mar;
117(20):5340-9.
PMID: 21403133
Micro-RNAs (miRNAs) have been recognized as critical regulators of gene expression, and deregulation of miRNA expression has been implicated in a wide spectrum of diseases. To provide a framework for...
4.
Spierings D, de Vries E, Vellenga E, van den Heuvel F, Koornstra J, Wesseling J, et al.
J Histochem Cytochem
. 2004 May;
52(6):821-31.
PMID: 15150291
Recombinant human (rh) TNF-related apoptosis-inducing ligand (TRAIL) harbors potential as an anticancer agent. RhTRAIL induces apoptosis via the TRAIL receptors TRAIL-R1 and TRAIL-R2 in tumors and is non-toxic to nonhuman...