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Dhelio B Pereira

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Articles 32
Citations 466
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Recent Articles
1.
Xie S, Tai C, Morton C, Ma L, Huang S, Wittlin S, et al.
PLoS Pathog . 2024 Dec; 20(12):e1012429. PMID: 39652589
The Plasmodium falciparum cytoplasmic tyrosine tRNA synthetase (PfTyrRS) is an attractive drug target that is susceptible to reaction-hijacking by AMP-mimicking nucleoside sulfamates. We previously identified an exemplar pyrazolopyrimidine ribose sulfamate,...
2.
Gomez-Gonzalez P, Gupta A, Drought L, Patel A, Okombo J, van der Watt M, et al.
Sci Adv . 2024 Dec; 10(49):eadq1383. PMID: 39642214
Cyclic nucleotide-dependent phosphodiesterases (PDEs) play essential roles in regulating the malaria parasite life cycle, suggesting that they may be promising antimalarial drug targets. PDE inhibitors are used safely to treat...
3.
Moreira H, Sgorlon G, Queiroz J, Roca T, Ribeiro J, Teixeira K, et al.
Microbiol Spectr . 2024 Feb; 12(3):e0162923. PMID: 38323826
Oropouche virus (OROV) is characterized as a re-emerging arbovirus of great concern for public health, being responsible for several outbreaks of acute fever identified in Latin American countries, registering more...
4.
Mehdipour P, Rajasekhar M, Dini S, Zaloumis S, Abreha T, Adam I, et al.
Malar J . 2023 Oct; 22(1):306. PMID: 37817240
Background: Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax. This study investigated the effect of reduced adherence on the risk of P. vivax recurrence....
5.
Commons R, Rajasekhar M, Edler P, Abreha T, Awab G, Baird J, et al.
Lancet Infect Dis . 2023 Sep; 24(2):172-183. PMID: 37748496
Background: Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal dosing regimen remains unclear. We undertook a systematic review and individual patient data meta-analysis to investigate the efficacy...
6.
Andrade A, Santos N, Bastos A, Pontual J, Araujo J, Silva A, et al.
PLoS Negl Trop Dis . 2023 Jun; 17(6):e0011425. PMID: 37327209
Malaria is caused by parasite of the genus Plasmodium and is still one of the most important infectious diseases in the world. Several biological characteristics of Plasmodium vivax contribute to...
7.
Fantin R, Coelho C, Berhe A, Magalhaes L, Pereira D, Salinas N, et al.
PLoS Negl Trop Dis . 2023 Apr; 17(4):e0011229. PMID: 37027391
Plasmodium vivax is a major challenge for malaria control due to its wide geographic distribution, high frequency of submicroscopic infections, and ability to induce relapses due to the latent forms...
8.
Trimarsanto H, Amato R, Pearson R, Sutanto E, Noviyanti R, Trianty L, et al.
Commun Biol . 2022 Dec; 5(1):1411. PMID: 36564617
Traditionally, patient travel history has been used to distinguish imported from autochthonous malaria cases, but the dormant liver stages of Plasmodium vivax confound this approach. Molecular tools offer an alternative...
9.
Cortopassi W, Gunderson E, Annunciato Y, Silva A, Dos Santos Ferreira A, Teles C, et al.
Int J Parasitol Drugs Drug Resist . 2022 Nov; 20:121-128. PMID: 36375339
Malaria is among the tropical diseases that cause the most deaths in Africa. Around 500,000 malaria deaths are reported yearly among African children under the age of five. Chloroquine (CQ)...
10.
Fantin R, Abeijon C, Pereira D, Fujiwara R, Bueno L, Campos-Neto A
Trop Med Infect Dis . 2022 Oct; 7(10). PMID: 36288055
Five species of cause malaria in humans and two of them, and , pose the greatest threat. Rapid antigen detection tests (RADT) have been used for many years to diagnose...