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Dezhao Lu

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Articles 38
Citations 354
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Recent Articles
1.
Zhu J, Yuan A, Le Y, Chen X, Guo J, Liu J, et al.
Phytomedicine . 2024 Nov; 135:156189. PMID: 39515100
Background: The kidneys are the primary excretory organs for platinum drugs, making them susceptible to damage from these drugs. Cisplatin-induced acute kidney injury (CIAKI) is the most common side effect...
2.
Yuan A, Liu J, Guo J, Chen F, Xu J, Chen H, et al.
J Agric Food Chem . 2024 Sep; 72(38):20959-20973. PMID: 39282743
Obesity-related metabolic diseases are associated with a chronic inflammatory state. Calenduloside E (CE) is a triterpene saponin from sugar beet. In mouse models, CE reduced pro-inflammatory cytokines in white adipose...
3.
Wang W, Shi X, Feng J, Le Y, Jin L, Lu D, et al.
J Hazard Mater . 2024 Sep; 479:135735. PMID: 39241360
Liver injury and inflammation are the most commonly observed adverse outcomes following exposure to penta-brominated flame retardants (penta-BFRs). However, the role of inflammation in the development of liver injury in...
4.
Zhu J, Guo J, Liu Z, Liu J, Yuan A, Chen H, et al.
Chem Biol Interact . 2024 Jul; 400:111162. PMID: 39047806
Non-alcoholic fatty liver disease (NAFLD) affects approximately a quarter of the population and, to date, there is no approved drug therapy for this condition. Individuals with type 2 diabetes mellitus...
5.
Guo J, Le Y, Yuan A, Liu J, Chen H, Qiu J, et al.
J Ethnopharmacol . 2024 Mar; 328:118080. PMID: 38521426
Ethnopharmacological Relevance: The use of antineoplastic drugs, such as cisplatin, in clinical practice can cause adverse effects in patients, such as liver injury, which limits their long-term use. Therefore, there...
6.
Jiang D, Guo J, Liu Y, Li W, Lu D
Front Immunol . 2024 Jan; 14:1327852. PMID: 38264652
Osteoarthritis (OA) has been a leading cause of disability in the elderly and there remains a lack of effective therapeutic approaches as the mechanisms of pathogenesis and progression have yet...
7.
Le Y, Guo J, Liu Z, Liu J, Liu Y, Chen H, et al.
J Ethnopharmacol . 2023 Sep; 319(Pt 2):117239. PMID: 37777027
Ethnopharmacological Relevance: Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition that can have multiple underlying causes. There are no satisfactory chemical or biological drugs for the treatment...
8.
Zhu J, Chen H, Le Y, Guo J, Liu Z, Dou X, et al.
Front Pharmacol . 2022 Nov; 13:1009229. PMID: 36425580
Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Bunge,...
9.
Zhu J, Chen H, Guo J, Zha C, Lu D
J Inflamm Res . 2022 Nov; 15:6293-6306. PMID: 36408328
Introduction: Atherosclerosis (AS) is the underlying cause of cardiovascular events. Endothelial cell mitochondrial damage and pyroptosis are important factors contributing to AS. Changes in internal mitochondrial conformation and increase in...
10.
Chen H, Zhu J, Le Y, Pan J, Liu Y, Liu Z, et al.
Phytomedicine . 2022 Feb; 99:153964. PMID: 35180677
Background: Doxorubicin-induced cardiotoxicity (DIC) limits the clinical application of the drug in treatment of cancers and imposes a severe health burden on the patients. Therefore, there is an urgent need...