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Dexiang Xu

Explore the profile of Dexiang Xu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 275
Followers 0
Related Specialties
Environmental Health
Toxicology
Pharmacology
Top 10 Co-Authors
Hua Wang
Cheng Zhang
Bingdong Song
Jun Fang
Chunyu Guo
Yuanhua Chen
Zhengmei Xia
Weirong Hu
Sujuan Zhao
Zhijing Lin
Published In
Sci Total Environ
Ecotoxicol Environ Saf
Environ Pollut
Acta Biomater
J Control Release
Affiliations
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Recent Articles
1.
Effect of Metagenomic Next-Generation Sequencing on Clinical Outcomes of Patients With Severe Community-Acquired Pneumonia in the ICU: A Multicenter, Randomized Controlled Trial
Wu X, Sun T, He H, Xing L, Cheng Z, Geng S, et al.
Chest . 2024 Jul; 167(2):362-373. PMID: 39067508
Background: Metagenomic next-generation sequencing (mNGS) was previously established as a method that can increase the pathogen identification rate in patients with severe community-acquired pneumonia (SCAP). Research Question: What is the...
2.
The Role of Oxidative Stress and DNA Hydroxymethylation in the Pathogenesis of Benzo[a]pyrene-Impaired Reproductive Function in Male Mice
Gan Y, Zhang X, Cai P, Zhao L, Liu K, Wang H, et al.
Environ Toxicol . 2024 Jul; 39(11):5039-5047. PMID: 39037180
Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon, is known to cause teratogenesis. Environmental exposure of BaP has led to wide public concerns due to their potential risk of reproductive toxicity. However,...
3.
C5b-9 promotes ferritinophagy leading to ferroptosis in renal tubular epithelial cells of trichloroethylene-sensitized mice
Liu Z, Zhou S, Wang F, Xie H, Zhang J, Wu C, et al.
Sci Total Environ . 2024 Mar; 923:171378. PMID: 38447712
Trichloroethylene (TCE) is a common environmental contaminant that can cause a severe allergic reaction called TCE hypersensitivity syndrome, which often implicates the patient's kidneys. Our previous study revealed that C5b-9-induced...
4.
Exploring the therapeutic potential of a nano micelle containing a carbon monoxide-releasing molecule for metabolic-associated fatty liver disease by modulating hypoxia-inducible factor-1α
Cui Y, Guo C, Xia Z, Xue Y, Song B, Hu W, et al.
Acta Biomater . 2023 Aug; 169:500-516. PMID: 37574157
Metabolic-associated fatty liver disease (MAFLD) encompasses a spectrum of chronic liver diseases, including steatohepatitis, cirrhosis, and liver cancer. Despite the increasing prevalence and severity of MAFLD, no approved pharmacological interventions...
5.
Sleep Deprivation and Heart Rate Variability in Healthy Volunteers: Effects of REM and SWS Sleep Deprivation
Xu Y, Qu B, Liu F, Gong Z, Zhang Y, Xu D
Comput Math Methods Med . 2023 Jul; 2023:7121295. PMID: 37469834
Objective: Using PSG-guided acute selective REM/SWS sleep deprivation in volunteers, this study examined the effects of sleep deprivation on the cardiovascular and autonomic nervous systems, as well as the relationship...
6.
Mononuclear myeloid-derived suppressor cells expansion is associated with progression of liver failure in patients with acute decompensation of cirrhosis
Yang B, Sun F, Chen Y, Shi C, Qi L, Yu F, et al.
Int Immunopharmacol . 2023 Jul; 122:110581. PMID: 37406396
Patients with acute decompensation (AD) of cirrhosis have different clinical courses. Immune dysfunction affects disease outcomes. The profile of myeloid-derived suppressor cells (MDSCs), polymorphonuclear- (PMN-MDSCs) and mononuclear- (M-MDSCs) subsets in...
7.
PM and its respiratory tract depositions on blood pressure, anxiety, depression and health risk assessment: A mechanistic study based on urinary metabolome
Yuan Z, Miao L, Yang L, Chen P, Jiang C, Fang M, et al.
Environ Res . 2023 Jun; 233:116481. PMID: 37364626
Effects of fine particulate matter (PM) and regional respiratory tract depositions on blood pressure (BP), anxiety, depression, health risk and the underlying mechanisms need further investigations. A repeated-measures panel investigation...
8.
Docosahexaenoic acid protects against lipopolysaccharide-induced fetal growth restriction via inducing the ubiquitination and degradation of NF-κB p65 in placental trophoblasts
Bo Q, Xie Y, Lin Q, Fu L, Hu C, Zhang Z, et al.
J Nutr Biochem . 2023 Apr; 118:109359. PMID: 37085060
Lipopolysaccharide (LPS) could induce adverse birth outcomes by evoking inflammation. We investigated the effect and mechanism of docosahexaenoic acid (DHA) on LPS-induced placental inflammation and fetal growth restriction (FGR). In...
9.
Polymeric nano-micelle of carbon monoxide donor SMA/CORM2 ameliorates acetaminophen-induced liver injury via suppressing HMGB1/TLR4 signaling pathway
Xue Y, Zhang D, Wei Y, Guo C, Song B, Cui Y, et al.
Eur J Pharm Sci . 2023 Mar; 184:106413. PMID: 36863618
Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of acute liver failure. Excessive generation of reactive oxygen species (ROS) and inflammatory responses are the major causes of necrosis and/or...
10.
Newly discovered developmental and ovarian toxicity of 3-monochloro-1,2-propanediol in Drosophila melanogaster and cyanidin-3-O-glucoside's protective effect
Cai Y, Liu Z, Gao T, Hu G, Yin W, Wang Y, et al.
Sci Total Environ . 2023 Mar; 874:162474. PMID: 36863584
3-Monochloro-1,2-propanediol (3-MCPD) is a pervasive environmental pollutant that is unintentionally produced during industrial production and food processing. Although some studies reported the carcinogenicity and male reproduction toxicity of 3-MCPD thus...