Devin T Wiley
Overview
Explore the profile of Devin T Wiley including associated specialties, affiliations and a list of published articles.
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4
Citations
277
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Recent Articles
1.
Chao J, Lin J, Frankel P, Clark A, Wiley D, Garmey E, et al.
J Gastrointest Oncol
. 2018 Jan;
8(6):962-969.
PMID: 29299355
Background: CRLX101 is an investigational nanoparticle-drug conjugate with a camptothecin payload. Preclinical evidence indicated preferential uptake in tumors, and tumor xenograft models demonstrate superiority of CRLX101 over irinotecan. A pilot...
2.
Clark A, Wiley D, Zuckerman J, Webster P, Chao J, Lin J, et al.
Proc Natl Acad Sci U S A
. 2016 Mar;
113(14):3850-4.
PMID: 27001839
Nanoparticle-based therapeutics are being used to treat patients with solid tumors. Whereas nanoparticles have been shown to preferentially accumulate in solid tumors of animal models, there is little evidence to...
3.
Eliasof S, Lazarus D, Peters C, Case R, Cole R, Hwang J, et al.
Proc Natl Acad Sci U S A
. 2013 Aug;
110(37):15127-32.
PMID: 23980155
Nanoparticles are currently being investigated in a number of human clinical trials. As information on how nanoparticles function in humans is difficult to obtain, animal studies that can be correlative...
4.
Wiley D, Webster P, Gale A, Davis M
Proc Natl Acad Sci U S A
. 2013 May;
110(21):8662-7.
PMID: 23650374
Receptor-mediated transcytosis across the blood-brain barrier (BBB) may be a useful way to transport therapeutics into the brain. Here we report that transferrin (Tf)-containing gold nanoparticles can reach the brain...