Devi Thiagarajan
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Explore the profile of Devi Thiagarajan including associated specialties, affiliations and a list of published articles.
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16
Citations
319
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Recent Articles
1.
Yepuri G, Ramirez L, Theophall G, Reverdatto S, Quadri N, Hasan S, et al.
Nat Commun
. 2023 Oct;
14(1):6900.
PMID: 37903764
Inter-organelle contact and communication between mitochondria and sarco/endoplasmic reticulum (SR/ER) maintain cellular homeostasis and are profoundly disturbed during tissue ischemia. We tested the hypothesis that the formin Diaphanous-1 (DIAPH1), which...
2.
Thiagarajan D, Quadri N, Jawahar S, Zirpoli H, Hurtado Del Pozo C, Lopez-Diez R, et al.
Obesity (Silver Spring)
. 2022 Jul;
30(8):1647-1658.
PMID: 35894077
Objective: Aldose reductase (AKR1B1 in humans; Akr1b3 in mice), a key enzyme of the polyol pathway, mediates lipid accumulation in the murine heart and liver. The study objective was to...
3.
Muniappan L, Okuyama M, Javidan A, Thiagarajan D, Jiang W, Moorleghen J, et al.
Arterioscler Thromb Vasc Biol
. 2021 Mar;
41(5):1694-1709.
PMID: 33761765
[Figure: see text].
4.
Javidan A, Jiang W, Okuyama M, Thiagarajan D, Yang L, Moorleghen J, et al.
Sci Rep
. 2019 Sep;
9(1):12626.
PMID: 31477775
miR-146a, an anti-inflammatory microRNA, is shown to be a negative regulator of adipocyte inflammation. However, the functional contribution of miR-146a in the development of obesity is not defined. In order...
5.
Colombo A, Zubair A, Thiagarajan D, Nuzhdin S, Triche T, Ramsingh G
Sci Rep
. 2018 Mar;
8(1):4240.
PMID: 29511219
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
6.
Dai X, Thiagarajan D, Fang J, Shen J, Annam N, Yang Z, et al.
PLoS One
. 2017 Dec;
12(12):e0190191.
PMID: 29284006
Vascular smooth muscle cell (VSMC) phenotypic modulation is characterized by the downregulation of SMC actin cytoskeleton proteins. Our published study shows that depletion of SM22α (aka SM22, Transgelin, an actin...
7.
OShea K, Ananthakrishnan R, Li Q, Quadri N, Thiagarajan D, Sreejit G, et al.
EBioMedicine
. 2017 Dec;
26:165-174.
PMID: 29239839
The biochemical, ionic, and signaling changes that occur within cardiomyocytes subjected to ischemia are exacerbated by reperfusion; however, the precise mechanisms mediating myocardial ischemia/reperfusion (I/R) injury have not been fully...
8.
Thiagarajan D, O Shea K, Sreejit G, Ananthakrishnan R, Quadri N, Li Q, et al.
PLoS One
. 2017 Dec;
12(11):e0188981.
PMID: 29190815
Aldose reductase (AR: human, AKR1B1; mouse, AKR1B3), the first enzyme in the polyol pathway, plays a key role in mediating myocardial ischemia/reperfusion (I/R) injury. In earlier studies, using transgenic mice...
9.
Colombo A, Zubair A, Thiagarajan D, Nuzhdin S, Triche T, Ramsingh G
Sci Rep
. 2017 Aug;
7(1):7029.
PMID: 28765607
Genomic transposable elements (TEs) comprise nearly half of the human genome. The expression of TEs is considered potentially hazardous, as it can lead to insertional mutagenesis and genomic instability. However,...
10.
Thiagarajan D, Vedantham S, Ananthakrishnan R, Schmidt A, Ramasamy R
Biochim Biophys Acta
. 2016 Aug;
1862(12):2221-2231.
PMID: 27543804
Acetylation of proteins as a post-translational modification is gaining rapid acceptance as a cellular control mechanism on par with other protein modification mechanisms such as phosphorylation and ubiquitination. Through genetic...