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Detlef Schuppan

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Articles 389
Citations 13305
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Recent Articles
1.
Schuppan D, Neufang S, Wanger B
Dtsch Med Wochenschr . 2025 Feb; 150(6):273-279. PMID: 39983762
Coeliac disease is the most common chronic inflammatory disease of the small intestine, with a prevalence of around 1% almost worldwide. It is caused by the consumption of cereals containing...
2.
Stolzel U, Jost L, Seehofer D, Egger-Heidrich K, Scheuermann U, Holig K, et al.
EJHaem . 2025 Feb; 6(1):e21092. PMID: 39967799
Introduction: Erythropoietic Protoporphyria (EPP) caused skin light sensitivity and liver cirrhosis in a 35-year-old patient who subsequently developed liver-failure. Methods: In absence of a human leukocyte antigens (HLA)-matched-unrelated donor, the...
3.
Younossi Z, Razavi H, Sherman M, Allen A, Anstee Q, Cusi K, et al.
Aliment Pharmacol Ther . 2025 Feb; PMID: 39967239
Background: The continuum of metabolic syndrome encompasses a spectrum of dysfunctions impacting obesity-linked insulin resistance, glucose homeostasis, lipid metabolism and pro-inflammatory immune responses. The global prevalence of metabolic diseases, including...
4.
Tsouka A, Fu Y, Ricardo M, Seeberger P, Wang Y, Pier G, et al.
Angew Chem Int Ed Engl . 2025 Feb; :e202420874. PMID: 39945485
Peptidoglycan (PGN) is a complex biopolymer crucial for cell wall integrity and function of all bacterial species. While the strong inflammatory properties of PGN and its derived muropeptides are well-documented...
5.
Bokemeyer B, Serdani-Neuhaus L, Sunwoldt J, Dunweber C, Schnaidt S, Schuppan D
Therap Adv Gastroenterol . 2025 Feb; 18:17562848251314803. PMID: 39906416
Background: Coeliac disease (CeD) is a chronic immune-mediated disease triggered by exposure to dietary gluten in genetically predisposed individuals. The burden of CeD on patients and the healthcare system remains...
6.
Kaps L, Genc M, Moehler M, Grabbe S, Schattenberg J, Schuppan D, et al.
BMC Gastroenterol . 2025 Feb; 25(1):53. PMID: 39905306
Background: The collagen-rich tumor stroma plays a crucial role in biliary tract cancer (BTC). Collagen biomarkers of type I collagen (reC1M), type III collagen (PRO-C3), type IV collagen (C4G), type...
7.
Vali Y, Dijk A, Lee J, Boursier J, Ratziu V, Yunis C, et al.
Liver Int . 2025 Jan; 45(2):e16240. PMID: 39865358
Background And Aims: The performance of non-invasive liver tests (NITs) is known to vary across settings and subgroups. We systematically evaluated whether the performance of three NITs in detecting advanced...
8.
Wu L, Huang X, Li F, Jiang S, Ni L, Ai Y, et al.
United European Gastroenterol J . 2024 Dec; PMID: 39740197
Background: It remains unclear whether the addition of non-selective beta-blockers (NSBB) provides further benefit after combined use of tissue adhesive and endoscopic variceal ligation for bleeding gastroesophageal varices. Objective: This...
9.
Lai M, Dillon S, Gu X, Morhardt T, Xu Y, Chan N, et al.
Hepatol Commun . 2024 Dec; 8(12). PMID: 39621304
Background: Reliable, noninvasive tools to diagnose at-risk metabolic dysfunction-associated steatohepatitis (MASH) are urgently needed to improve management. We developed a risk stratification score incorporating proteomics-derived serum markers with clinical variables...
10.
Lange S, Tsohataridis S, Boland N, Ngo L, Hahad O, Munzel T, et al.
Nutrients . 2024 Jul; 16(14). PMID: 39064708
Introduction: The exposome concept includes nutrition as it significantly influences human health, impacting the onset and progression of diseases. Gluten-containing wheat products are an essential source of energy for the...