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Despina Siolas

Explore the profile of Despina Siolas including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 954
Followers 0
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Recent Articles
1.
Metzger D, Greenspun B, Siolas D, Jafari M
Ann Surg Oncol . 2025 Feb; PMID: 40009308
No abstract available.
2.
Metzger D, Greenspun B, Brouwer J, Li Y, Pigazzi A, Siolas D, et al.
Ann Surg Oncol . 2025 Feb; PMID: 39948314
Background: Whereas clinicopathologic risk factors for colon cancer (CC) recurrence are well-established, the role of genomic predictors remains understudied. This study aimed to identify genomic factors associated with recurrence after...
3.
McIntyre C, Grimont A, Park J, Meng Y, Sisso W, Seier K, et al.
Cancer Cell . 2024 Aug; 42(9):1614-1629.e5. PMID: 39214094
KRAS mutations in pancreatic ductal adenocarcinoma (PDAC) are suggested to vary in oncogenicity but the implications for human patients have not been explored in depth. We examined 1,360 consecutive PDAC...
4.
Narayan V, Siolas D, Meadows E, Turzhitsky V, Sillah A, Imai K, et al.
JCO Clin Cancer Inform . 2023 Oct; 7:e2300096. PMID: 37906722
Purpose: Treatment of non-muscle-invasive bladder cancer (NMIBC) is guided by risk stratification using clinical and pathologic criteria. This study aimed to develop a natural language processing (NLP) model for identifying...
5.
Kasi P, Hidalgo M, Jafari M, Yeo H, Lowenfeld L, Khan U, et al.
Oncogene . 2023 Sep; 42(44):3252-3259. PMID: 37731056
In patients with locally advanced cancer without distant metastases, the neoadjuvant setting presents a platform to evaluate new drugs. For mismatch repair proficient/microsatellite stable (pMMR/MSS) colon and rectal cancer, immunotherapy...
6.
Wan S, Zhao E, Freeman D, Weissinger D, Krantz B, Werba G, et al.
Front Immunol . 2023 Apr; 14:1177713. PMID: 37033968
[This corrects the article DOI: 10.3389/fimmu.2023.1067352.].
7.
Wan S, Zhao E, Weissinger D, Krantz B, Werba G, Freeman D, et al.
Front Immunol . 2023 Feb; 14:1067352. PMID: 36798126
Hepato-pancreatico-biliary (HPB) malignancies are difficult-to-treat and continue to to have a high mortality and significant therapeutic resistance to standard therapies. Immune oncology (IO) therapies have demonstrated efficacy in several solid...
8.
Siolas D, Vucic E, Kurz E, Hajdu C, Bar-Sagi D
Cell Rep . 2021 Aug; 36(8):109578. PMID: 34433022
Tumor genotype can influence the immune microenvironment, which plays a critical role in cancer development and therapy resistance. However, the immune effects of gain-of-function Trp53 mutations have not been defined...
9.
Yin L, Criscito M, Stokar E, Siolas D, Haimovic A, Lo Sicco K, et al.
Am J Dermatopathol . 2021 Jun; 43(10):746-749. PMID: 34086644
Papillary dermal elastolysis has been described in the setting of experimental combination nivolumab and cabiralizumab immunotherapy. We report a third patient with distinctive, generalized atrophic macules that developed after a...
10.