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Derrick Zhao

Explore the profile of Derrick Zhao including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 387
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Recent Articles
1.
Zeng J, Way G, Wu N, Jiang X, Tai Y, Zhao D, et al.
Cell Biosci . 2025 Mar; 15(1):34. PMID: 40057751
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses various conditions, ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. MASLD is a significant risk factor for...
2.
Way G, Lu H, Wang X, Zhao D, Camarena C, Sarkar D, et al.
Liver Res . 2025 Feb; 7(3):263-271. PMID: 39958386
The liver plays an important role in both metabolism and immunity. Disruption of the hepatic immune microenvironment is closely associated with various liver diseases. To gain a better understanding of...
3.
Jackson K, Zhao D, Su L, Lipp M, Toler C, Idowu M, et al.
Hepatol Commun . 2025 Jan; 8(12. PMID: 39773902
Background: Sphingosine-1 phosphate (S1P) is a bioactive lipid molecule that modulates inflammation and hepatic lipid metabolism in MASLD, which affects 1 in 3 people and increases the risk of liver...
4.
Zeng J, Zhao D, Way G, Fagan A, Fuchs M, Puri P, et al.
JCI Insight . 2025 Jan; 10(4). PMID: 39773539
Cirrhosis, the end-stage of liver disease, progresses through altered gut-liver axis and microbial change. Here we show that intestinal mucosal mitochondrial oxidative phosphorylation, which affects intestinal barrier worsens with cirrhosis...
5.
Aseem S, Way G, Wang J, Zhao D, Tai Y, Gurley E, et al.
bioRxiv . 2024 Nov; PMID: 39574583
Background: Fibroinflammatory cholangiopathies, such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), are characterized by inflammation and biliary fibrosis, driving disease-related complications. In biliary fibrosis, cholangiocytes activated by...
6.
Oshins R, Greenberg Z, Tai Y, Zhao D, Wang X, Mehrad B, et al.
bioRxiv . 2024 Sep; PMID: 39229038
Liver fibrosis associated with increased mortality is caused by activation of hepatic stellate cells and excessive production and accumulation of extracellular matrix in response to fibrotic insults. It has been...
7.
Wang Y, Zhao D, Su L, Tai Y, Way G, Zeng J, et al.
Cell Biosci . 2024 Jan; 14(1):14. PMID: 38273376
Background And Aims: Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by progressive biliary inflammation and bile duct injury. Berberine (BBR) is a bioactive isoquinoline alkaloid found in...
8.
Wolstenholme J, Saunders J, Smith M, Kang J, Hylemon P, Gonzalez-Maeso J, et al.
Nat Commun . 2022 Oct; 13(1):6198. PMID: 36261423
Alcohol use disorder is a major cause of morbidity, which requires newer treatment approaches. We previously showed in a randomized clinical trial that alcohol craving and consumption reduces after fecal...
9.
Wang Y, Tai Y, Way G, Zeng J, Zhao D, Su L, et al.
Cell Biosci . 2022 Oct; 12(1):172. PMID: 36224648
Background: NAFLD has become the most common chronic liver disease worldwide. Human antigen R (HuR), an RNA-binding protein, is an important post-transcriptional regulator. HuR has been reported as a key...
10.
Xue R, Su L, Lai S, Wang Y, Zhao D, Fan J, et al.
Cells . 2021 Nov; 10(11). PMID: 34831031
The prevalence of nonalcoholic fatty liver disease (NAFLD) has been significantly increased due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH)...