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Derrick Morgan

Explore the profile of Derrick Morgan including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 153
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Recent Articles
1.
Catozzi A, Peiris-Pages M, Humphrey S, Revill M, Morgan D, Roebuck J, et al.
bioRxiv . 2024 Feb; PMID: 38405859
Molecular subtypes of Small Cell Lung Cancer (SCLC) have been described based on differential expression of transcription factors (TFs) , and immune-related genes. We previously reported an additional subtype based...
2.
Pearsall S, Williamson S, Humphrey S, Hughes E, Morgan D, Garcia Marques F, et al.
J Thorac Oncol . 2023 Jul; 18(10):1362-1385. PMID: 37455012
Introduction: Vasculogenic mimicry (VM), the process of tumor cell transdifferentiation to endow endothelial-like characteristics supporting de novo vessel formation, is associated with poor prognosis in several tumor types, including SCLC....
3.
Shue Y, Drainas A, Li N, Pearsall S, Morgan D, Sinnott-Armstrong N, et al.
Nat Commun . 2022 May; 13(1):2690. PMID: 35577801
The Notch pathway is a conserved cell-cell communication pathway that controls cell fate decisions. Here we sought to determine how Notch pathway activation inhibits the neuroendocrine cell fate in the...
4.
Simpson K, Stoney R, Frese K, Simms N, Rowe W, Pearce S, et al.
Nat Cancer . 2022 Feb; 1(4):437-451. PMID: 35121965
Although small cell lung cancer (SCLC) is treated as a homogeneous disease, biopsies and preclinical models reveal heterogeneity in transcriptomes and morphology. SCLC subtypes were recently defined by neuroendocrine transcription...
5.
Pearsall S, Humphrey S, Revill M, Morgan D, Frese K, Galvin M, et al.
J Thorac Oncol . 2020 Jul; 15(12):1836-1843. PMID: 32721553
Introduction: Recent consensus defines four SCLC subtypes on the basis of transcription factor expression: ASCL1, NEUROD1, POU2F3, and YAP1. The rare YAP1 subtype is associated with "neuroendocrine (NE)-low" cells among...
6.
Jones H, Reens J, Brocklehurst S, Betts C, Bickerton S, Bigley A, et al.
Int J Exp Pathol . 2014 Jan; 95(1):29-48. PMID: 24456331
Antagonism of the effects of glucagon as an adjunct therapy with other glucose-lowering drugs in the chronic treatment of diabetes has been suggested to aggressively control blood glucose levels. Antagonism...