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Deric L Wheeler

Explore the profile of Deric L Wheeler including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 2362
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Recent Articles
1.
Crossman B, Harmon R, Kostecki K, McDaniel N, Iida M, Corday L, et al.
J Clin Med . 2024 Oct; 13(20). PMID: 39457986
Head and neck squamous cell carcinoma (HNSCC) is diagnosed in more than 71,000 patients each year in the United States, with nearly 16,000 associated deaths. One significant hurdle in the...
2.
Mirzapoiazova T, Tseng L, Mambetsariev B, Li H, Lou C, Pozhitkov A, et al.
iScience . 2024 Jul; 27(6):110132. PMID: 38993482
Although up to 80% small cell lung cancer (SCLC) patients' response is good for first-line chemotherapy regimen, most patients develop recurrence of the disease within weeks to months. Here, we...
3.
Iida M, Crossman B, Kostecki K, Glitchev C, Kranjac C, Crow M, et al.
Int J Mol Sci . 2024 May; 25(10). PMID: 38791148
Triple-negative breast cancer (TNBC) is characterized by the absence of the estrogen receptor, progesterone receptor, and receptor tyrosine kinase HER2 expression. Due to the limited number of FDA-approved targeted therapies...
4.
Kostecki K, Iida M, Crossman B, Salgia R, Harari P, Bruce J, et al.
Cancers (Basel) . 2024 Jan; 16(2). PMID: 38254801
Head and neck cancers (HNCs) arise from the mucosal lining of the aerodigestive tract and are often associated with alcohol use, tobacco use, and/or human papillomavirus (HPV) infection. Over 600,000...
5.
Berube L, Nickel K, Iida M, Ramisetty S, Kulkarni P, Salgia R, et al.
Semin Radiat Oncol . 2023 Jun; 33(3):279-286. PMID: 37331782
Patient-derived cancer models have been used for decades to improve our understanding of cancer and test anticancer treatments. Advances in radiation delivery have made these models more attractive for studying...
6.
Poellmann M, Bu J, Kim D, Iida M, Hong H, Wang A, et al.
Cancer Lett . 2023 Apr; 562:216187. PMID: 37068555
Head and neck squamous cell carcinoma (HNSCC) is a common and deadly cancer. Circulating tumor cell (CTC) abundance may a valuable, prognostic biomarker in low- and intermediate-risk patients. However, few...
7.
Wang Y, Li W, Li Z, Mo F, Chen Y, Iida M, et al.
Sci Adv . 2023 Mar; 9(13):eadf6854. PMID: 36989364
Immune checkpoint inhibitors (ICIs) can reinvigorate T cells to eradicate tumor cells, showing great potential in combating various types of tumors. We propose a delivery strategy to enhance tumor-selective ICI...
8.
Kostecki K, Iida M, Wiley A, Kimani S, Mehall B, Tetreault K, et al.
Head Neck . 2023 Mar; 45(5):1255-1271. PMID: 36939040
Background: The tyrosine kinase receptors Axl and MerTK are highly overexpressed in head and neck cancer (HNC) cells, where they are critical drivers of survival, proliferation, metastasis, and therapeutic resistance....
9.
Toulany M, Iida M, Lettau K, Coan J, Rebholz S, Khozooei S, et al.
Radiother Oncol . 2022 Jul; 174:92-100. PMID: 35839938
Background: AKT1 must be present and activated in the nucleus immediately after irradiation to stimulate AKT1-dependent double-strand breaks (DSB) repair through the fast non-homologous end-joining (NHEJ) repair process. We investigated...
10.
Iida M, McDaniel N, Kostecki K, Welke N, Kranjac C, Liu P, et al.
BMC Cancer . 2022 Apr; 22(1):447. PMID: 35461210
Background: The receptor tyrosine kinase (RTK) epidermal growth factor receptor (EGFR) is overexpressed and an important therapeutic target in Head and Neck cancer (HNC). Cetuximab is currently the only EGFR-targeting...