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Derek Wallace

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Articles 33
Citations 1171
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Fernando L, Kastner R, Wickramasinghe P, Fernando A, Gunasekera D, Nguyen V, et al.
PLoS Negl Trop Dis . 2024 Aug; 18(8):e0012376. PMID: 39173075
Background: Outbreaks of dengue can overburden hospital systems, drastically reducing capacity for other care. The 2017 dengue serotype 2 (DENV-2) outbreak in Sri Lanka coincided with vaccination in an ongoing...
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Sirivichayakul C, Biswal S, Saez-Llorens X, Lopez-Medina E, Borja-Tabora C, Bravo L, et al.
J Infect Dis . 2024 Apr; 230(6):e1214-e1225. PMID: 38682569
Background: We explored the impact of prior yellow fever (YF) or Japanese encephalitis (JE) vaccination on the efficacy of Takeda's dengue vaccine candidate, TAK-003. Methods: Children 4-16 years of age...
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Tricou V, Yu D, Reynales H, Biswal S, Saez-Llorens X, Sirivichayakul C, et al.
Lancet Glob Health . 2024 Jan; 12(2):e257-e270. PMID: 38245116
Background: About half of the world's population lives in dengue-endemic areas. We aimed to evaluate the long-term efficacy and safety of two doses of the tetravalent dengue vaccine TAK-003 in...
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Tricou V, Winkle P, Tharenos L, Rauscher M, Escudero I, Hoffman E, et al.
Vaccine . 2023 Oct; 41(47):6999-7006. PMID: 37884415
Background: We conducted a trial to demonstrate immunogenic equivalence of three consecutive manufacturing lots of Takeda's tetravalent dengue vaccine candidate, TAK-003, and further assessed its safety and reactogenicity. Methods: Healthy...
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Tricou V, Essink B, Ervin J, Turner M, Escudero I, Rauscher M, et al.
PLoS Negl Trop Dis . 2023 Mar; 17(3):e0011124. PMID: 36888687
Background: Yellow fever (YF) vaccination is often mandatory for travelers to YF-endemic areas. The areas with risk of YF partially overlap with those of dengue, for which there is currently...
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Saez-Llorens X, Biswal S, Borja-Tabora C, Fernando L, Liu M, Wallace D, et al.
Am J Trop Med Hyg . 2023 Mar; 108(4):722-726. PMID: 36878213
In the pivotal phase 3 efficacy trial (NCT02747927) of the TAK-003 dengue vaccine, 5 of 13,380 TAK-003 recipients and 13 of 6,687 placebo recipients experienced two episodes of symptomatic dengue...
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Tricou V, Eyre S, Ramjee M, Collini P, Mojares Z, Loeliger E, et al.
Vaccine . 2023 Jan; 41(7):1398-1407. PMID: 36681529
Background: Vaccination against hepatitis A virus (HAV) is largely recommended for travelers worldwide. Concurrent dengue and HAV vaccination may be desired in parallel for travelers to countries where both diseases...
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Tricou V, Gottardo R, Egan M, Clement F, Leroux-Roels G, Saez-Llorens X, et al.
Vaccine . 2022 Jan; 40(8):1143-1151. PMID: 35078666
Background: As robust dengue-specific CD4+ and CD8+ T cell responses are essential for protective immunity, we assessed cell-mediated immune (CMI) responses to a DENV-2-based dengue tetravalent vaccine candidate (TAK-003) in...
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Rivera L, Biswal S, Saez-Llorens X, Reynales H, Lopez-Medina E, Borja-Tabora C, et al.
Clin Infect Dis . 2021 Oct; 75(1):107-117. PMID: 34606595
Background: Takeda's live attenuated tetravalent dengue vaccine candidate (TAK-003) is under evaluation in a long-term clinical trial across 8 dengue-endemic countries. Previously, we have reported its efficacy and safety in...