Derek Thirstrup
Overview
Explore the profile of Derek Thirstrup including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
1022
Followers
0
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Related Specialties
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Recent Articles
1.
McQuin C, Goodman A, Chernyshev V, Kamentsky L, Cimini B, Karhohs K, et al.
PLoS Biol
. 2018 Jul;
16(7):e2005970.
PMID: 29969450
CellProfiler has enabled the scientific research community to create flexible, modular image analysis pipelines since its release in 2005. Here, we describe CellProfiler 3.0, a new version of the software...
2.
Dey J, Dubuc A, Pedro K, Thirstrup D, Mecham B, Northcott P, et al.
Cancer Res
. 2013 Oct;
73(22):6828-37.
PMID: 24092238
While medulloblastoma, a pediatric tumor of the cerebellum, is characterized by aberrations in developmental pathways, the majority of genetic determinants remain unknown. An unbiased Sleeping Beauty transposon screen revealed MyoD...
3.
Brownell J, Wagoner J, Lovelace E, Thirstrup D, Mohar I, Smith W, et al.
J Hepatol
. 2013 Jun;
59(4):701-8.
PMID: 23770038
Background & Aims: The pro-inflammatory chemokine CXCL10 is induced by HCV infection in vitro and in vivo, and is associated with outcome of IFN (interferon)-based therapy. We studied how hepatocyte...
4.
Mehan M, Ayers D, Thirstrup D, Xiong W, Ostroff R, Brody E, et al.
PLoS One
. 2012 Apr;
7(4):e35157.
PMID: 22509397
Lung cancer remains the most common cause of cancer-related mortality. We applied a highly multiplexed proteomic technology (SOMAscan) to compare protein expression signatures of non small-cell lung cancer (NSCLC) tissues...
5.
Gupta S, Thirstrup D, Jarvis T, Schneider D, Wilcox S, Carter J, et al.
Appl Immunohistochem Mol Morphol
. 2011 Jan;
19(3):273-8.
PMID: 21217521
Immunohistochemistry is used in both research and clinical settings to identify proteins in tissue samples. Despite the power and versatility of immunohistochemistry, limitations are imposed by the slow diffusion of...
6.
Eaton S, Wiktor P, Thirstrup D, Lake D, Nagaraj V
Biochem Biophys Res Commun
. 2010 Dec;
405(1):1-6.
PMID: 21167816
In this study we investigated E6 and E7 oncogenes from the Human Papilloma Virus as targets for siRNA knockdown in order to boost the efficacy of the anti-cancer drug 'tumor...
7.
Thirstrup D, Baird G
Anal Chem
. 2010 Feb;
82(6):2498-504.
PMID: 20166673
The enzyme horseradish peroxidase is routinely used in immunohistochemistry to facilitate the chromogenic oxidation of 3,3'-diaminobenzidine, producing an insoluble brown precipitate marking the location and quantity of a tissue protein....
8.
Nagaraj V, Eaton S, Thirstrup D, Wiktor P
Biochem Biophys Res Commun
. 2008 Aug;
375(4):526-30.
PMID: 18718447
Glycans have great potential as disease biomarkers and therapeutic targets. However, the major challenge for glycan biomarker identification from clinical samples is the low abundance of key glycosylated proteins. To...