Derek N J Hart
Overview
Explore the profile of Derek N J Hart including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
64
Citations
1955
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fromm P, Silveira P, Hsu J, Papadimitrious M, Lo T, Ju X, et al.
J Leukoc Biol
. 2019 Nov;
107(2):323-339.
PMID: 31749181
Myeloid lineage cells present in human peripheral blood include dendritic cells (DC) and monocytes. The DC are identified phenotypically as HLA-DR cells that lack major cell surface lineage markers for...
2.
Abadir E, Gasiorowski R, Lai K, Kupresanin F, Romano A, Silveira P, et al.
Mol Oncol
. 2019 Jul;
13(10):2107-2120.
PMID: 31338922
Antibody-based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic...
3.
Li Z, Ju X, Silveira P, Abadir E, Hsu W, Hart D, et al.
Front Immunol
. 2019 Jun;
10:1312.
PMID: 31231400
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune...
4.
Lo T, Abadir E, Gasiorowski R, Kabani K, Ramesh M, Orellana D, et al.
PLoS One
. 2019 May;
14(5):e0216368.
PMID: 31075107
Acute myeloid leukemia (AML) is the most common form of adult acute leukemia with ~20,000 new cases yearly. The disease develops in people of all ages, but is more prominent...
5.
Clark G, Silveira P, Hogarth P, Hart D
Semin Cell Dev Biol
. 2018 Mar;
86:3-14.
PMID: 29499385
Dendritic cells (DC) are bone marrow derived leucocytes that are part of the mononuclear phagocytic system. These are surveillance cells found in all tissues and, as specialised antigen presenting cells,...
6.
Bryant C, Sutherland S, Kong B, Papadimitrious M, Fromm P, Hart D
Semin Cell Dev Biol
. 2018 Feb;
86:77-88.
PMID: 29454038
The ability of immune therapies to control cancer has recently generated intense interest. This therapeutic outcome is reliant on T cell recognition of tumour cells. The natural function of dendritic...
7.
Li Z, Ju X, Lee K, Clarke C, Hsu J, Abadir E, et al.
Haematologica
. 2018 Jan;
103(4):655-665.
PMID: 29351987
Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory...
8.
Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al.
J Immunol
. 2016 Nov;
197(12):4613-4625.
PMID: 27837105
CD83 is a member of the Ig gene superfamily, first identified in activated lymphocytes. Since then, CD83 has become an important marker for defining activated human dendritic cells (DC). Several...
9.
Fromm P, Papadimitrious M, Hsu J, Van Kooten Losio N, Verma N, Lo T, et al.
Oncoimmunology
. 2016 Jul;
5(6):e1168555.
PMID: 27471645
There are numerous transcriptional, proteomic and functional differences between monocyte-derived dendritic cells (Mo-DC) and primary blood dendritic cells (BDC). The CMRF-56 monoclonal antibody (mAb) recognizes a cell surface marker, which...
10.
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al.
J Immunol
. 2016 Jun;
197(3):885-98.
PMID: 27316686
C-type lectin receptors play important roles in immune cell interactions with the environment. We described CD302 as the simplest, single domain, type I C-type lectin receptor and showed it was...