Derek Chalmers
Overview
Explore the profile of Derek Chalmers including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
221
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0
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Recent Articles
1.
Thomsen W, Grottick A, Menzaghi F, Reyes-Saldana H, Espitia S, Yuskin D, et al.
J Pharmacol Exp Ther
. 2008 Feb;
325(2):577-87.
PMID: 18252809
5-Hydroxytryptamine (5-HT)(2C) receptor agonists hold promise for the treatment of obesity. In this study, we describe the in vitro and in vivo characteristics of lorcaserin [(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3 benzazepine], a selective, high...
2.
Apone F, Alyeshmerni N, Wiens K, Chalmers D, Chrispeels M, Colucci G
Plant Physiol
. 2003 Sep;
133(2):571-9.
PMID: 12972659
Different lines of evidence suggest that specific events during the cell cycle may be mediated by a heterotrimeric G-protein activated by a cognate G-protein coupled receptor. However, coupling between the...
3.
McLean A, Zeng F, Behan D, Chalmers D, Milligan G
Mol Pharmacol
. 2002 Aug;
62(3):747-55.
PMID: 12181453
Constitutive activity of wild-type and mutant forms of human beta(1)- and beta(2)-adrenoceptors was measured by guanosine 5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPgammaS) binding assays using fusion proteins between these receptors and G(s)alpha. Constitutive activity...
4.
Colucci G, Apone F, Alyeshmerni N, Chalmers D, Chrispeels M
Proc Natl Acad Sci U S A
. 2002 Apr;
99(7):4736-41.
PMID: 11930019
Although signaling through heterotrimeric G proteins has been extensively studied in eukaryotes, there is little information about this important signaling pathway in plants. We observed that expression of GCR1, the...