Derek Best
Overview
Explore the profile of Derek Best including associated specialties, affiliations and a list of published articles.
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28
Citations
260
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Recent Articles
1.
Drop J, Van Den Helm S, Letunica N, Wildschut E, de Hoog M, de Boode W, et al.
Pediatr Crit Care Med
. 2025 Mar;
26(3):e315-e323.
PMID: 40048299
Objectives: To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed according...
2.
Cai T, Emery-Corbin S, McCafferty C, Van Den Helm S, Letunica N, Attard C, et al.
Pediatr Crit Care Med
. 2024 Aug;
25(11):1017-1025.
PMID: 39145643
Objective: To characterize surface-bound proteins and to measure the thickness of fibrin fibers bound to extracorporeal membrane oxygenation (ECMO) circuits used in children. Design: Single-center observational prospective study, April to...
3.
Cai T, Emery-Corbin S, McCafferty C, Van Den Helm S, Letunica N, Barton R, et al.
ASAIO J
. 2024 Jul;
PMID: 39008796
No abstract available.
4.
Cai T, Burton M, McCafferty C, Van Den Helm S, Letunica N, Attard C, et al.
ASAIO J
. 2024 Jun;
71(1):e1-e4.
PMID: 38905612
The continuous contact between blood and the foreign surface of the extracorporeal membrane oxygenation (ECMO) circuit contributes to hemostatic, inflammatory, and other physiological disturbances observed during ECMO. Although previous studies...
5.
Pan K, Namachivayam S, Chiletti R, Best D, Horton S, Butt W
ASAIO J
. 2024 Feb;
70(8):698-703.
PMID: 38417432
Nitric oxide (NO) can be safely delivered through the sweep gas to the oxygenator of an extracorporeal membrane oxygenation (ECMO) circuit. It has theoretical benefits such as preventing platelet adhesion...
6.
Drop J, Letunica N, Van Den Helm S, van Ommen C, Wildschut E, de Hoog M, et al.
Res Pract Thromb Haemost
. 2024 Jan;
7(8):102252.
PMID: 38193071
Background: Extracorporeal membrane oxygenation (ECMO) is used in children with cardiopulmonary failure. While the majority of ECMO centers use unfractionated heparin, other anticoagulants, including factor XI and factor XII inhibitors...
7.
Van Den Helm S, Letunica N, Barton R, Weaver A, Yaw H, Karlaftis V, et al.
Pediatr Crit Care Med
. 2023 Jan;
24(4):268-276.
PMID: 36602314
Objectives: To investigate changes in von Willebrand factor (VWF) concentration, function, and multimers during pediatric extracorporeal membrane oxygenation (ECMO) and determine whether routine monitoring of VWF during ECMO would be...
8.
Van Den Helm S, Yaw H, Letunica N, Barton R, Weaver A, Newall F, et al.
Crit Care Med
. 2022 Jan;
50(8):1236-1245.
PMID: 35020670
Objectives: To investigate platelet pathophysiology associated with pediatric extracorporeal membrane oxygenation (ECMO). Design: Prospective observational study of neonatal and pediatric ECMO patients from September 1, 2016, to December 31, 2019....
9.
Best D, Millar J, Kornilov I, Sinelnikov Y, Chiletti R, Rycus P, et al.
Perfusion
. 2017 Oct;
32(7):609-612.
PMID: 28985704
Kawasaki disease is usually a limited illness of early childhood. However, life-threatening cardiac manifestations can occur, either at acute presentation or as a consequence of coronary arterial involvement. We report...
10.
Cortina G, Best D, Deisenberg M, Chiletti R, Butt W
Arch Dis Child Fetal Neonatal Ed
. 2017 Oct;
103(4):F370-F376.
PMID: 28970319
Objective: To describe the effect of extracorporeal membrane oxygenation (ECMO) on survival and cardiac outcome of neonates with myocardial failure secondary to severe enterovirus (EV) myocarditis. Design: Retrospective case series....